Adrenergic and Anti-Adrenergic Drugs Flashcards
1
Q
What are the two classes of adrenergic drugs
A
- Adrenergic agonist - stimulate effects of adrenergic nerve activity
- Adrenergic antagonist- block effects of adrenergic nerve activity
2
Q
What are sympathomimetics?
A
Substance that cause the activation of adrenoreceptors and mimic the actions of catecholamines.
3
Q
3 catecholamines
A
- Norepinephrine
- Epinephrine
- Dopamines
4
Q
MOA of direct acting sympathomimetics
A
- Act via a direct mode
- interact DIRECTLY with adrenoreceptors and ACTIVE them
5
Q
MOA of indirect acting sympathomimetics
A
Action depend of the release of endogenous catecholamines:
Increase the release of endogenous catecholamines by:
- increasing presynaptic release
- inhibiting re-uptake.
6
Q
Locations of B1 adrenoreceptors
A
Heart
Salivary Gland
7
Q
Location of B2 adrenoreceptors
A
Blood vessels Brochi GIT Uterus Bladder Iris Cillary muscle
8
Q
Location of A1 receptors
A
Blood vessels Bronchi GIT Uterus Bladder Iris
9
Q
Location A2 adrenoreceptors
A
Blood vessels
Bronchi
GIT
