Adrenergic 1 Flashcards

1
Q

Agents that enhance or reduce the activity of the sympathetic division

A

Adrenergic agents

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2
Q

Metabolites are not dound in urine T/F

A

False (Found in urine)

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3
Q

Adrenergic agonist are derivatives of what?

A

Beta phenlyethylamine

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4
Q

Sympathomimetic amines contain 3,5 -dihydroxybenzene T/F

A

False: 3,4 dihydroxybenzene

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5
Q

OH that shows the highest potency in activation of a and b

A

3,4

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6
Q

Cathecholomines have good penetration into the cns T/F

A

False: has poor penetration

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7
Q

The addition of this at amino nitrogen enhances the beta receptor activity

A

Isopropyl (isoproterenol)

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8
Q

The larger the substituent on the amino group, the lover the activity at alpha receptors T/F

A

True

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9
Q

Other name for alpha-methyl compounds

A

Phenylisopropylamines

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10
Q

Clonidine is an aminoimidazoline T/F

A

True

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11
Q

It is converted to alpha-methyl norepinephrine
Used for treating essential HTN

A

Methyldopa (aldomet)

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12
Q

It is a synthetic catecholamine

A

Dobutamine

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13
Q

In dobitamine, the + isomer is a potent beta 1 agonist and the - isomer is a potent alpha agonist T/F

A

True

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14
Q

It increases beta 2 activity in terbutaline

A

3,5 dihydroxy

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15
Q

An IV drug for severe hypertension
Selectively leads to peripheral vasodilation

A

Fenaldopam

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16
Q

Immediate precursor to norepinephrine
Activates d1 that leads to vasodilation

A

Dopamine

17
Q

It is the first orally active sypathomimetic drug
Non-cathecol

A

Ephedrine

18
Q

A CNS stimulant that is indirect acting sympathomimetic

A

Amphetamine

19
Q

Drugs used in children with attention deficit hyperactive

A

Methylphenidate
Pemoline

20
Q

Phenylpropanolamine is associated with hemorrhagic stroke

A

True

21
Q

Found in fermented food

A

Tyramine

22
Q

Patients taking MAO-inhibitors should avoid tyramine

A

True

23
Q

Plant alkaloid that blocks Mg/ATP transport

A

Reserpine

24
Q

An adrenergic neuron blocker thst blocks the release of Norepinephrine

A

Guanethidine

25
Q

Beta 1 selectives are those with p-substituents and no meta substituent rings

A

True

26
Q

It is the most lipophilic of the Non-selective beta blockers

A

Propanolol

27
Q

Exame.of beta blockers with alpha 1 antagonist activity

A

Labetalol
Carvedilol