Adrenergic 1 Flashcards
Agents that enhance or reduce the activity of the sympathetic division
Adrenergic agents
Metabolites are not dound in urine T/F
False (Found in urine)
Adrenergic agonist are derivatives of what?
Beta phenlyethylamine
Sympathomimetic amines contain 3,5 -dihydroxybenzene T/F
False: 3,4 dihydroxybenzene
OH that shows the highest potency in activation of a and b
3,4
Cathecholomines have good penetration into the cns T/F
False: has poor penetration
The addition of this at amino nitrogen enhances the beta receptor activity
Isopropyl (isoproterenol)
The larger the substituent on the amino group, the lover the activity at alpha receptors T/F
True
Other name for alpha-methyl compounds
Phenylisopropylamines
Clonidine is an aminoimidazoline T/F
True
It is converted to alpha-methyl norepinephrine
Used for treating essential HTN
Methyldopa (aldomet)
It is a synthetic catecholamine
Dobutamine
In dobitamine, the + isomer is a potent beta 1 agonist and the - isomer is a potent alpha agonist T/F
True
It increases beta 2 activity in terbutaline
3,5 dihydroxy
An IV drug for severe hypertension
Selectively leads to peripheral vasodilation
Fenaldopam
Immediate precursor to norepinephrine
Activates d1 that leads to vasodilation
Dopamine
It is the first orally active sypathomimetic drug
Non-cathecol
Ephedrine
A CNS stimulant that is indirect acting sympathomimetic
Amphetamine
Drugs used in children with attention deficit hyperactive
Methylphenidate
Pemoline
Phenylpropanolamine is associated with hemorrhagic stroke
True
Found in fermented food
Tyramine
Patients taking MAO-inhibitors should avoid tyramine
True
Plant alkaloid that blocks Mg/ATP transport
Reserpine
An adrenergic neuron blocker thst blocks the release of Norepinephrine
Guanethidine
