Adrenal Disease 2

Question 1

What is Conn’s syndrome? What is it also known as?

Answer 1

Excess mineralocorticoid

Also known as primary hyperaldosteronism

Question 2

What effect does Conn’s have on the body?

Answer 2

Increased sodium and water retention, increased potassium elimination (–> weakness, polyuria), low renin

Question 3

What is the main clinical presentation of Conn’s?

Answer 3

Hypertension (due to increased sodium and water retention)

Question 4

What is the treatment for Conn’s?

Answer 4

Surgery to remove tumour or spironolactone (aldosterone receptor antagonist)