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Adverse Drug Reactions > ADR-CIOMS > Flashcards

ADR-CIOMS Flashcards

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Organic Chemistry 101 flashcards
1
Q

Superficial skin inflammation

A

Dermatitis or eczema

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2
Q

TRUE OR FALSE

Are dermatitis and eczema synonymous?

A

TRUE

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3
Q

Synonym for exfoliative dermatitis

A

Erythroderma

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4
Q

Redness and scaling of skin that may be life-threatening

A

Exfoliative dermatitis

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5
Q

Skin or mucosal eruption characterized by solitary or multiple oval erythematous patches with dark colored centers

A

Fixed drug eruptions

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6
Q

Subacute violaceous papular/plaque eruption

A

Lichenoid drug eruption

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7
Q

Synonyms of pustular eruption

A

Pustuloderma
Pustular rashes
Acute generalized exanthemic pustulosis

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8
Q

Small sterile pustules arising on edematous painful erythema

A

Pustular eruption

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9
Q

Swelling of the skin from the dermis with white center and red edge

A

Wheals

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10
Q

Involves deeper dermal and subcutaneous tissues; same as urticaria

A

Angioedema

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11
Q

Synonyms of angioderma

A

Quincke’s edema

Angioneurotic edema

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12
Q

Skin eruption consisting of multiple transient wheals with itching

A

Urticaria

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13
Q

Eruption with larger edematous wheals that involves the dermal layers

A

Angioedema

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14
Q

Synonyms of erythema multiforme

A

Erythema exudativum

Erythema exudativum multiforme

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15
Q

Synonym of toxic epidermal necrolysis

A

Lyell’s syndrome

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16
Q

Symmetrically distributed papular lesions in the extremities with mucosal erosions; target shaped lesions

A

Erythema multiforme

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17
Q

Erythematous macules with epidermal detachment; do not exceed 10% of bsa

A

Steven-johnson syndrome

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18
Q

Widespread erythematous areas with epithelial necrosis and epidermal detachment >10% bsa

A

Toxic epidermal necrolysis

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19
Q

Exaggerated sunburn reaction

A

Photosensitivity reaction

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20
Q

Exaggerated sunburn like reactions from photosensitizing substance

A

Phototoxic reactions

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21
Q

Pleomorphic immunologically mediated skin reactions

A

Photoallergic reactions

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22
Q

Pimple-like small lesions

A

Papule

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23
Q

Flat erythematous

A

Macule

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24
Q

Elevated/map-like

A

Plaque

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25
Q

Flat/ bigger macule

A

Patch

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26
Q

Pus/ sterile

A

Pustule

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27
Q

Contains liquid

A

Vesicle

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28
Q

Bigger vesicle/ large mass

A

Bullae

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29
Q

Fracture of damaged or diseased bone

A

Pathological fracture

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30
Q

Disorder of striated muscle
With muscle pain
Tenderness

A

Myopathy

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31
Q

Inflammation of striated muscle with muscle weakness

A

Myositis

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32
Q

TRUE OR FALSE

Myositis is synonymous to myalgia

A

FALSE

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33
Q

Inflammatory changes with predominant lymphocytic infiltration

A

Polymyositis

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34
Q

A characteristic heliotropic rash

A

Dermatomysitis

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35
Q

Low bone mass and microarchitectural deterioration of bone tissue

A

Osteoporosis

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36
Q

Collagen vascular disease with a wide range of rheumatic manifestations affecting multiple organ systems

Autoimmune abnormalities

A

Lupus erythematosus syndrome

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37
Q

Synonym of LE syndrome

A

Systemic lupus erythematosus

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38
Q

Fixed erythema, flat or raised over malar eminences

A

Malar rash

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39
Q

Erythematous raised patches with adherent keratotic scaling and follicular plugging

A

Discoid rash

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40
Q

Oral or nasopharyngeal ulceration

A

Oral ulcers

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41
Q

Tenderness, swelling or effusion of peripheral joints

A

Arthritis

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42
Q

Other name for retroperitoneal fibrosis

A

Ormond’s disease

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43
Q

Fibrosis of organs or tissues in the retroperitoneal space compressing the ureters and other structures

A

Retroperitoneal fibrosis

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44
Q

Necrotizing inflammatory lesion of blood vessels— occlusion or disruption

A

Vasculitis

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45
Q

Dysfunction of the autonomic parasympathetic system

A

Anticholinergic syndrome

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46
Q

Abnormal movements with chorea and athetosis

With abnormal gait and speech difficulties

A

Choreoathetosis

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47
Q

Ceaseless occurence of well coordinated involuntary arrythmic jerky movements of limbs face muscles tongue

A

Chorea

48
Q

Abnormal slow sinuous writhing-type movements

A

Athetosis

49
Q

Abrupt and involuntary contraction of skeletal muscles

A

Convulsions

50
Q

Abnormal movement related to extrapyramidal function

Impairment of voluntary control

A

Dyskinesia

51
Q

Excessive nonrhythmic involuntary uncontrolled movements

A

Hyperkinesia

52
Q

Diminished and ultimately absent movements

A

Hypokinesia

Akinesia

53
Q

Slow movement

A

Bradykinesia

54
Q

Rhythmic hyperkinesia

A

Tremor

55
Q

Any impairment of the voice

A

Dysphonia

56
Q

Slow or sustained abnormal movements appearing as abnormal postures

A

Dystonia

57
Q

Late persistent dystonia

A

Tardive dyskinesia

58
Q

Any chronic degenerative disease of the brain

A

Encephalopathy

59
Q

Disturbance of motor function caused by lesions or dysfunctions of the extrapyramidal motor system

A

Extrapyramidal disorder

60
Q

Impaired posture and movement when walking

A

Abnormal gait

61
Q

Synonyms of hypertonia

A

Increased muscular tone

62
Q

Velocity-dependent increase in muscular tone

A

Spasticity

63
Q

Increased resistance to passive movement

A

Rigidity

64
Q

Synonyms of hypotonia

A

Flaccidity
Diminished tone
Floppiness

65
Q

Decrease or loss of muscular tone

Decrease or loss of resistance to passive movement

A

Hypotonia

66
Q

Life threatening condition associated with tx with neuroleptic drugs

A

Neuroleptic malignant syndrome

67
Q

Impairment of the peripheral motor sensory and autonomic nervous system

A

Neuropathy

68
Q

Abrupt involuntary upward or sideward torsion of eyeballs and elevation of upper eyelids

A

Oculogyric crisis

69
Q

Synonyms of oculogyric crisis

A

Oculogyric spasms

Eye spasms

70
Q

Transient or permanent complete loss of muscle function

A

Paralysis

71
Q

Incomplete paralysis

A

Paresis

72
Q

Cluster of signs of motor autonomic and mental disturbances indicative of serotonergic function

A

Serotonin syndrome

73
Q

Any impairment in fluidity rhythm tone or articulation of words

A

Speech disorder

74
Q

Congenital or acquired lack of clarity of the lens

A

Cataract

75
Q

Lesions of the cornea

A

Keratitis

76
Q

Abnormalities of the retina

A

Retinal disorder

77
Q

Deterioration in visual function or perception

A

Vision abnormal

78
Q

Cochlear or vestibular dysfunction

A

Ototoxicity

79
Q

Major manifestations of ototoxicity

A

Hearing loss
Tinnitus
Vertigo

80
Q

Loss of appetite for food

A

Anorexia

81
Q

Decrease of appetite

A

Hyporexia

82
Q

Mental disorder characterized by refusal to maintain body weight at above normal weight

A

Anorexia nervosa

83
Q

Absence of emotional responsiveness or indifference to surroundings or reduced reactivity to stimuli

A

Apathy

84
Q

Synonyms of apathy

A

Indifference
Lack of feelings
Emotional unresponsiveness
Emotionless

85
Q

Confusional state of acute onset

Distorted or reduced attention

A

Delirium

86
Q

Alteration in the experience and awareness of self

A

Depersonalization

87
Q

Morbid mental state dominated by lowering of mood

A

Depression

88
Q

Mental disturbance characterized by loss of contact with reality

A

Psychotic reaction

89
Q

Changes in the speed of ideation and association processes

A

Thought disturbances

90
Q

Pain in the topographical area of the abdomen

A

Abdominal pain

91
Q

Inflammation of the colon

With diarrhea and fecal blood or leukocytes

A

Colitis

92
Q

Colitis confined to the rectum

A

Proctitis

93
Q

Widening of the subepithelial collagen layer of the colon

A

Colitis collagenous

94
Q

Passage of hard stools

Difficulty or less frequent defecation

A

Constipation

95
Q

Passage of loose unformed stools

A

Diarrhea

96
Q

Group of symptoms of various disorders of the alimentary tract

A

Dyspepsia

97
Q

Inflammation of the gastric mucosa

A

Gastritis

98
Q

Bleeding of any degree in the GI tract

A

Gastrointestinal hemorrhage

99
Q

Death of intestinal tissue

A

Intestinal necrosis

100
Q

Infected necrosis

A

Gangrene

101
Q

Vomiting of fresh or altered blood

A

Hematemesis

102
Q

Anal passage of bright red blood

A

Hematochezia

103
Q

Lack of intestinal peristalsis

A

Ileus

104
Q

Inadequate oxygenation of the small intestine or colon

A

Intestinal ischemia

105
Q

Occurrence of a mechanical impediment to the progression of the content of the intestinal lumen

A

Intestinal obstruction

106
Q

Perforation of all the layers of the wall of the stomach or intestine

A

Intestinal perforation to

107
Q

Pathological narrowing of the lumen of the intestine

A

Intestinal stenosis

108
Q

Passage of black stools

A

Melena

109
Q

Inflammatory disease of the pancreas with abdominal pain

A

Acute pancreatitis

110
Q

Recurrent or persisting abdominal pain in the pancreas char

A

Chronic pancreatitis

111
Q

Non neoplastic focal destructive lesion penetrating the mucosal layer in the GI where there is acid and peptic activity

A

Peptic ulcer

112
Q

Inflammation of the peritoneum

A

Peritonitis

113
Q

Localized or generalized inflammation of the buccal mucosa

A

Stomatitis

114
Q

Single or multiple ulcers in the oral mucosa

A

Ulcerative stomatitis

115
Q

Ulcer in the esophagus

A

Esophageal ulcer

116
Q

Ulcer in the first part of the duodenum

A

Duodenal ulcer

Adverse Drug Reactions (1 decks)

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