ADR Flashcards

1
Q

ADR of NK1 antagonists

A

Fatigue, weakness
Nausea
Hiccups

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2
Q

Drug interactions with NK1 antagonists

A

3A4 inhibitor: contraception, steroids, benzos
2C9 inducer: warfarin, sulfonylureas
Chemo drugs: ifosfamide (reduced metabolism of ifosfamide)

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3
Q

ADR of 5HT3 antagonists

A

Headache
Constipation
QTc prolongation

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4
Q

ADR of dexamethasone

A

Transient increase in glucose
Insomnia, anxiety
Gastric upset
Psychosis
Reactivation of GI ulcers

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5
Q

ADR of olanzapine

A

Fatigue
Sedation
Orthostasis
Anticholinergic ADR

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6
Q

ADR of metoclopramide

A

Sedation
Diarrhea
EPS

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7
Q

ADR of benzodiazepines

A

Drowsiness
Dizziness
Hypotension
Anterograde amnesia
Paradoxical agitation
Caution in elderly

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8
Q

ADR of octreotide

A

Bradycardia
Arrhythmias
Headache
Dizziness
Nausea/vomiting
Constipation
Abdo pain
Enlarged thyroid

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