Adolescent Med and Gyne - 2019 Updated! Flashcards
Parents come to you worried that their teenaged son has a problem with alcohol.
What are four signs of problem drinking in teenagers?
● CRAFT Mnemonic designed to screen for adolescents’ substance use in primary setting= CAR,
RELAX, ALONE, FORGET, FAMILY and FRIENDS, TROUBLE= During the past 12 months…
o Ridden in car driven by someone (incld. Yourself) who was high or had been using
alcohol or drugs?
o Used drugs to relax, feel better about yourself, or fit in?
o Used alcohol or drugs while you were by yourself?
o Ever forget things you did while using alcohol or drugs?
o Family and friends ever tell you to cut down your drinking or drug use?
o Ever gotten into trouble while using alcohol or drugs?
14 year old with genital pain and mild headache. On exam, you find two 0.5 cm ulcers in the inside of the labia majora. Besides herpes simplex virus, what 4 diagnoses should you consider?
- Syphilis
- Bechets
- Crohns
- Lipshutz ulcer (non infectious genital ulcer)
- Chancroid (caused by haemophilia ducrey)
- EBV or mycoplasma
Gardasil vaccine - what age is it recommended and what do you tell mom about need for routine pap smears when she is an adult
2 dose schedule for children age 9-14 years 6 months apart
3 dose schedule >=15 years
Pap - Age 25
2 dose schedule for children age 9-14 years 6 months apart
3 dose schedule >=15 years
Pap - Age 25,
The 5As of motivational interviewing for smoking cessation
Ask Advise Assess Assist Arrange
What is on the differential diagnosis for eating disorder?
Differential (CBC, ESR, lytes, Ca, Mg, PO, VBG, TSH, ECG +/-LFTS, albumin, lipids, cortisol, LH/FSH) - GI - IBD - Celiac - Infectious Gastroenteritis - HIV, TB - Endocrine - Hyper/Hypothyroidism - DM - Addison’s - Hypopituitarism - Psychiatric - OCD - Substance Use - Other - CNS lesions - SMA
16 yo boy has admitted to using anabolic steroids. His testes appear small.
1) Why are his testes small? (1 line)
2) What test(s) would you do to confirm your suspicion of why testes are small.?
1) Anabolic steroid-induced hypogonadism
Exogenous steroid suppresses the hypothalamic-pituitary axis, thus decreasing the release FSH/LH = decrease stimulation to produce endogenous testosterone and spermatogenesis, thus decreasing size of testes
2) Test to confirm: LH/FSH, Testosterone (total and free)
- Teenager with painful menses. What medication do you offer? List the dose, frequency and the
mechanism by which this medication works.
NSAIDs (ibuprofen 200mg q4-6h) - prostaglandin synthetase inhibitor
OCPs (low dose, cyclic) - inhibition of ovulation eliminates progesterone production OR decrease of endometrial lining thickness decreased prostaglandin production
Guidance counselor calls you about 12 y.o. from Inuit population. Thinks he may have ADHD. Give
four other things on your differential diagnosis.
● Neurodevelopmental: ASD, FASD, Fragile X, Specific LD
● Psych : Depression, Anxiety, Neglect,
● Neuro: Seizure disorder,
● Hearing or vision impairment
● Substance abuse
● Other organic: Iron deficiency anemia, Sleep apnea, lead poisoning
A 13 year old girl presents with a history of significant weight loss crossing percentiles, with normal height and otherwise normal exam. She has always been a picky eater, but now her repertoire of foods that she will eat has decreased even further. She has no history of purging.
1) What are the TWO elements of history that would help to determine what kind of eating disorder this girl has? (2 points)
2) What is the differential diagnosis (2 points)
1)
- Fear of gaining weight
- weight or shape has undue influence on self-evaluation
- lack of seriousness of current low weight
2) ARFID, Anorexia Nervosa, EoE
- Teenager, sexually active, pruritic genital lesions. On exam there are macules and plaques with erythema, crusting and blue-grey 3-5 mm papules.
What is the diagnosis (1). What is your treatment (1)
● Pediculosis Pubis ( pubic lice, aka “crabs”)
- examine all areas with coarse hair (eyelashes, eyebrows, beard, axilla, perianal area)
● tx: manually remove lice and their eggs (or hair shaved to limit infestation)
● tx: 1% permethrin cream rinse
- treat eyelash lice with petrolatum ointment 2-4x daily x10 days
● prevention: very contagious
○ machine-wash bedding, towels, clothes in hot water; dry in hot dryer
○ vacuum home, including mattresses
○ avoid sexual contact until successfully treated
○ tell all sex partners in last month about pubic lice
Skin change seen in anorexia nervosa:
a) lanugo
b) eczema
c) acne
d) alopecia
a) lanugo
- Girl started menarche 10 months ago, irregular every 1-3 months and heavy flow. No dysmennorhea.
What is the most likely cause and name 2 suggestions for management.
Immature HPG axis (no LH surge mid cycle leads to anovulation and abnormal bleeding)
- ddx: ectopic pregnancy, threatened abortion, endometritis
- mgmt: iron supplementation
- reassurance that expect this to resolve with time given only 10 months post menarchal and likely have anovulatory cycles
- consider OCPs
14 year old male with 3cm unilateral tender breast swelling. What do you do?
Ultrasound
F/U in 6mo
karyotype
CT scan
b. F/U in 6mo
Pubertal Gynecomastia
- Up to 60% of males
- Transient imbalance of estrogen and androgen
- Onset 10-13y (SMR 3-4)
- Usually regresses within 18-24 mo
A 15 year old otherwise healthy female is sexually active and comes in for a annual health check. According to the Greig health record, which of the following should she get:
- Chlamydia, gonorrhea testing
- Chlamydia, gonorrhea and HIV testing
- Chlamydia, gonorrhea, HIV testing and Pap smear
- Chlamydia, gonorrhea and HIV testing
But should also consider Syphillis
Which of the following is found more commonly in patients with bulimia nervosa
compared with anorexia nervosa:
a) cachexia
b) hypothermia
c) low blood pressure
d) enlarged salivary glands
e) extremely dry skin
d) enlarged salivary glands
A teenager is suspected of having depression by her parents. What five questions would you ask her to make your diagnosis of depression.
1) Sad Mood **
2) Anhedonia? ***
3) Guilty-feeling?
4) Energy level low, Sleep changes
5) Concentration difficulties
6) Appetitie – poor vs. hyperphagic
7) Psychomotor slowing
8) Suicidal ideation
15 year old boy with a history of significant school absenteeism. He has had symptoms of intermittent
abdominal pain and recently has developed daily headaches with onset in the later afternoon. He
continues to get As despite missing 40% of the days in school. His height and weight continue along the
same percentiles as previously. What is the most likely diagnosis:
a. Anxiety
What is post-OCP amenorrhea? how is it managed?
Most have menses in 30 days, almost all within 90 days.
- failure to resume menstruation within six months after discontinuation of oral contraceptives
- mgmt: only needed if pregnancy desired - bromocriptine and clomiphene; otherwise reassure (do rule out pituitary tumours and endo abnormalities)
Kid with signs of increased ICP, teased at school because of obesity and acne. PE reveals papilledema, MRI head normal. No sexual activity.
What is the most likely cause?
- Oral contraceptive
- Minocycline
b. Minocycline ( tetracycline Abx, used for acne, AE include raised ICP (IIH), bleeding, oliguria, N/V,
pancreatitis and skin rashes)
13 y.o with menometrorrhagia for 6 months. Menarche at 11 y.o. Bleeding x 3 weeks.
Causes of menorrhagia and irregular periods in an adolescent?
- estrogen deficiency
- progesterone excess
- continued endometrial proliferation
- ectopic pregnancy
- Von Willebrand’s disease
Continued endometrial proliferation.
*consider heme issue if periods are regular but heavy
In early postmenarchal years - most common cause of AUB is an ovulation (HPO axis’s is immature) . no midcycle surge of LH to stimulate ovulation -> no corpus luteum production of progesterone. W/O progesterone effects of stabilizing the endometrial lining, increased risk of irregular bleeding
Girl on Plan B vomits 90 minutes after dose. What do you tell her?
a. Take another dose now
b. Repeat in 12 hours with gravol
c. Does not need anymore doses
c. Does not need anymore doses
IF they vomit <1hr after taking dose of EC then retake it. If more than 1 hour then do not need to repeat.
A girl with anxiety wants to be taken off of her SSRI because of side effects. You:
a) Discontinue it right away
b) Discontinue it slowly to avoid withdrawl symptoms
c) Discontinue it and replace with benzdodiazepines
d) Discontinue it slowly to avoid serotonin syndrome
b) Discontinue it slowly to avoid withdrawl symptoms
Pt treated with prozac for 2 years. What is the chance of recurrence of depression once she is taken off this medication.
1. 10%
2. 20% 3. 40% 4. 75% 5. 90%
- 40%
Response rates to SSRIs in the treatment of depression are 40-70%.
- once treatment started, should continue for 6-12 months to decrease relapse risk
- risk of recurrence is 34-50% in first year after discontinuation
The most important reason to be concerned about adolescent alcohol abuse is:
a. Risk-taking behaviour while drinking
b. Depression associated with alcohol use
c. Liver disease
d. Poor school performance
a. Risk-taking behaviour while drinking
Options for emergency contraception
Hormonal: May be effective up to 5 days later.
- Levonorgestrel : single dose 1.5 mg, or 2 doses 0.75mg q12h (Plan B). Not as effective for BMI > 25
- Yuzpe (estrogen+progestin) - more SE.
- ELLA (Ulipristal acetate 30mg) - only by Rx. Okay for high BMI. Delay in next menses (can cause anxiety).
Non-Hormonal
- Copper IUD - effective if used within 7 days
15yo M with symptomatic urethritis, homosexual, yellow discharge when glans compressed?
a) what is the most likely
b) list 4 other causes
a) N. gonorrhea
b)
Chlamydia trichromatis
Trichomonas vaginalis
mycoplasma genitalium, ureaplasma urealyticum
HSV
Adenovirus
Trauma - contact with spermicide, recent instrumentation, vigorous sexual activity
Idiopathic
Which medication class causes sexual dysfunction in adolescents?
a) calcium channel blockers
b) antidepressants
c) beta-2 agonists
d) theophylline
b) antidepressants (specifically SSRIs)
You are treating a 17-year-old male for gonorrhea. Before treating his 15 year old female partner, what additional steps should you take?
A) get consent from her parents
B) get consent from her parents and then treat
C) inform child protection authorities
D) no steps needed
d) No steps needed
What are side effects of Plan B (Levonorgestrel)?
o side effects: headache, fatigue, nausea, dizziness
A teenage boy admits to having violent thoughts that overwhelm him. He says the thoughts are frequent and that he has not hurt anyone yet but fears he will soon. What diagnosis is most likely?
Behavioural problem
OCD
Schizophrenia
Antisocial personality
b. OCD - thoughts are egodystonic
List three things that are part of diagnosis of Autism.
1) Deficits in social communication and interaction across multiple contexts
2) Restricted, repetitive patterns of behaviour, interests, or activities.
3) Symptoms present in early development period
4) Symptoms cause clinically significant impairment in social/occupational/other important areas of functioning.
A description is given of an early-adolescent girl who is overweight. She is wondering what her ideal body weight should be. What is considered a normal BMI for her age.
normal BMI is between 5th to 85th percentile
- A mother who has been abused as a child asks you about advice for preventing child abuse. What is
the evidence
a. Nurse home visitor program reduces the risk of child abuse
b. Parenting classes reduce risk
c. Frequent visits to paediatrician can reduce risk
a. nurse home visitor program reduces the risk of child abuse
Child abuse can be prevented by: supportive family environments and supportive social networks,
parental employment, adequate housing, access to healthcare and social services
- 15 year old boy with T1DM. You can only follow him in your clinic until 18 years of age. 5 things you
would do to try to help him transition to adult care.
- See teens without parents for part of appointment
- Give increasing levels of responsibility and information
- Teach skills of negotiation and communication required in the adult system
- Providing a transition letter explaining the location of the new facility, staff and what to
expect - Collaboration with GPs and adult care provider
DSM V criteria for bulimia nervosa
- A. episodes of binge eating
- eating more than what most would eat
- lack of control
- B. compensatory behaviours (vomiting, laxatives, diuretics, medications,
fasting, exercise) - C. 1x/wk x3 mo
- D. self-eval influenced by shape and weight
- E. not AN
- Stage of remission
What is the most frequent cause of school absence in teenage girls:
(b) dysmenorrhea
A 13 year old boy presents to your office with a history of being argumentative with his teachers at school, skipping class and refusing to obey his parents rules at home. What is the most likely diagnosis? Name 2 treatment modalities that may be beneficial in this situation.
Oppositional Defiant Disorder
- triple P positive parenting program; CBT, family therapy
- medications: stimulants (for co-morbid ADHD) or atypical antipsychotics (risperidone)
A mother is concerned that her thirteen year old boy has recently started spending more time in his room, he is more tired and has difficulty awaking in the morning. He doesn’t participate in sports, and spends all of his time on his computer or with his friends. He is doing just below the average in school. When you speak to him, he says he smokes occasionally but denies any other alcohol or drug use. What do you do next:
A) Psychological assessment
B) Trial of stimulant medication
C) Reassure
A) Psychological assessment
Causes of abnormal uterine bleeding?
Broad strokes categories:
- ovulatory dysfunction
- coagulopathy
- NYD
Most critical finding in anorexia nervosa
- HR 40
- Hypokalemia
- temp >35
- Hypokalemia - Has risk of torsades and can be a sign of refeeding syndrome.
15 year old girl with frequent brief attacks where she feels short of breath and vaguely uneasy.
Which of the following would support your diagnosis:
a) Fear of episodes recurring and sudden onset of episodes
b) Family history of OCD
c) History of emotional trauma
d. Fear of episodes recurring and sudden onset of episodes (panic attacks)
A 15 year old girl comes to you for emergency contraception. Besides the fact that she may have significant nausea with the pill, you tell her the following in your counseling:
a) If she has a period in about 3 weeks there is no need for a pregnancy test
b) She will have a period in about 2 weeks and should have a pregnancy test
c) She will have menstrual bleeding in 2 to 3 days
a)If she has a period in about 3 weeks there is no need for a pregnancy test
F/U: A routine follow-up office visit is not required. With any form of emergency contraception, a pregnancy test should be performed to exclude the possibility of an intrauterine or ectopic pregnancy if bleeding has not occurred within three to four weeks or if there is abdominal pain or irregular bleeding
- 13 year old girl is sexually active. She sees you and has a normal pap smear with no STIʼs and uses
barrier protection. She doesn’t want you to tell her parents. What do you do? (3 lines)
Counsel on safe sex practices, encourage the use of oral contraception and reassure that you will not
speak to her parents about this. She is entitled to complete confidentiality unless there is a situation that
may harm her or harm others
Which anti epileptic medication is made less effective when taken with combined hormonal OCP?
lamotrigine, phenytoin, carbamazepine, topiramate
- VPA is NOT affected
Girl with PTSD – list 4 characteristics of PTSD
exposure to significant event
+ intrusive symptoms (e.g. flashbacks, dreams)
+ avoid triggers (thought,
memory, feeling, people, places)
+ negative cognition and mood (forget, anhedonia, detachment)
+ hyperarousal or
hypervigilance (reckless, irritable, startled easily)
- duration > 1 month
- clinically significant distress or functional impairment
Teenage girl with trisomy 21 is interested in Depo-provera. Name 2 long term side effects to this medication.
decreased BMD
amenorrhea
weight gain (though 20-40% may lose wt)
A 7 year old girl presents with vulvar pruritis. On exam, her labia minora and the skin of her perineum is white, shiny and thin, with a few scattered petechiae.
a. What is your likely diagnosis?
b. How would you treat?
c. What other 2 causes of vulvar itching in a pre-pubertal girl?
a. Lichen schlerosis
b. Topical steroid cream: Clobetasol 0.05% daily x 3 mos
c. Pinworms, vulvovaginitis
Medical reasons to admit a patient with anorexia?
- Physical
- HR <50 bpm awake (<45 asleep)
- BP < 80/50
- Rhythm disturbance/ Prolonged QT
- Orthostatic (BP >10, HR >25)
- <75-80% healthy body weight (or ongoing wt loss despite Rx)
- Laboratory
- Hypokalemia
- Hypophosphatemia
- Hypoglycemia
- Hypochloremia (BN)
- Liver, cardiac, renal compromise
What are features of refeeding syndrome?
Refeeding syndrome (intracellular shift of phosphate)
- most common in 1st week, with enteral nutrition
- low PO, K, Mg
- CHF and neurologic sx
- risky if <80% of expected weight for height
Teenager with PID. Cervical discharge and adnexal tenderness. Best treatment is:
1) IV cefoxitin and po doxycycline for 7 days
2) penicillin
3) Probenecid
IV cefoxitin and po doxycycline for 7 days
(should be 14 day course)
For MILD:
- CTX 250 mg x 1 IM and
Doxy 100 mg BID x 14 days and ± metro 500 mg BID
8 year old with ODD.
a. List 2 non pharmacological strategies.
b. What are 3 psychiatric comorbidities?
a. Parenting Training Program, Social competence training, Family based therapy, Academic engagement + skills building, Youth anger management, Social skills + problem solving training
- classroom based management
- daily routine and structure
b. ADHD, Anxiety, Depression, Substance use disorders, specific learning disorder
- What is the most common presentation of Chlamydia in a postpubertal adolescent?
a. Cervicitis
b. Asymptomatic
c. PID
d. vaginitis
b) asymptomatic
- up to 75% of women with chlamydia have no symptoms
- asymptomatic urethral infection is common in men
- can cause urethritis, epididymitis, cervicitis, salpingitis, proctitis, PID
- less acute symptoms compared to gonorrhea (mucoid discharge, not purulent)
16y sexually active male referred for scrotal mass/swelling: associated dull ache, on exam there is an irregular mass palpable in the left scrotum that increases when standing (no vitals given). The left testis is of normal size. diagnosis:
Spermatocele
Inguinal hernia
Epididymitis
varicocele
Varicocele
- Dull ache
- Heaviness
- Often on the Left
- “bag of worms” when palpated
A 15 year old female in your practice is about to become sexually active. When does she need her first gynecological exam including pap smear?
Pap smears now not recommended until age 25 q3years
An adolescent is in the ED who is 65% of her ideal body weight. HR 40, T35.8, BP 90/P. What to do:
- Slow refeeding- at risk for refeeding <80% of ideal body weight
A 6 y/o boy with 2 weeks of sudden onset of OCD behaviours. Which infectious agent would you be
concerned about:
- Strep pneumonia
- Group A Strep
- E. Coli
- H. Flu
- Echovirus
- Group A Strep - team Pandas is back!
PANDAS - pediatric autoimmune neuropsychiatric disorder associated with strep infection
- sudden onset neuropsychiatric disorders (particularly OCD, tic, tourettes) with possible
relationship with GAS- hypothesized (not proven)
How do you treat endometriosis?
leuprolide: create an environment of acyclic low dose estrogen to prevent bleeding and further seeding into the pelvis
An adolescent girl with diabetes for the last ten years is seen in diabetes follow up clinic. Her HbA1c is 7.6%. She is a straight A student. She has no complaints. Her weight has dropped from the 25th to the 5th percent. What is the most likely cause of her symptoms?
Eating disorder
Celiac disease
Hypothyroidism
Eating disorder
Factors that make a youth more likely to quit
Older teen Male Teen pregnancy + parenthood Scholastic success Team sports Peer and family support Low nicotine metabolizer
Diagnostic criteria for PID?
Lower abdominal pain + either cervical motion tenderness, uterine tenderness or adnexal tenderness
- if you have this in an adolescent female, treat on spec for PID
Diagnostic Criteria for ADHD:
≥ 6 Inattentive:
- Careless mistakes
- Doesn’t pay attention
- Doesn’t listen
- Doesn’t follow-through
- Not organized
- Loses things
- Distracted
- Forgetful
≥ Hyperactivity
- Can’t sit still
- Fidgets
- Runs about
- Can’t play quiet
- Driven by a motor
- Talks excessively
- Burts out answers
- Can’t wait turn
- Interrupts others
Mixed is ≥ 6 in both categories
Present in >1 setting
Present before 12 years
Functional impairment
A teenage boy is having difficulties functioning because he constantly has to watch his hands and has obsessive thoughts.
Which of the following medications may help him?
- Amitryptiline
- Clonazepam
- Clozapine
- Fluoxetine
- Fluoxetine - SSRI first line
Second line - Atypical antipsychotic or clomipramine (TCA)