Adjuvant Therapies Flashcards
Gabapentinoids
Generic and Brand
Gabapentin (Neurontin)
Pregabalin (Lyrica)
Gabapentinoid Uses
Fibromyalgia
Neuropathies
Post-Op
Gabapentinoid Dose Forms
Tablet
ER Tablet
Liquid Solution
Pregabalin Dosing
Lyrica- 75 mg PO BID (Max 600 mg/day)
Neurontin Dosing
100-300 mg PO TID
(max 3600 mg/day)
Clinical Pearls of Gabapentinoids
Renally
Titrate UP
Use in combo
Pregab schedule 5
SNRIs
Generic and Brand
Venlafaxine (Effexor)
Duloxetine (Cymbalta)
SNRI Uses
Fibromyalgia
Neuropathies
SNRI Dose Forms
Capsule/Tablet
ER as well^
Effexor Dosing
37.5-75 mg PO daily (max 225 mg/day)
Cymbalta Dosing
30 mg PO daily x 1 week- Then increase to 60 mg PO daily
(max 60 mg/day)
SNRI Pearls
titrate up
Venlafaxine renal adjustment
Duloxetine C/I in CrCl <30
TCA’s
Brand And Generic
Amitriptyline
(Elavil)
Nortriptyline (Pamelor)
TCA uses
Fibromyalgia
Neuropathies
Migraine Prophylaxis
TCA’s Dose Form
Tablet, Capsule, Oral Solution