ADHD drugs Flashcards
AX ROD T6 50/50 IRR
amphetamine
Adzeny’s XR ODT: 50/50 % IR/XR
ok for 6 yos
Adzeny’s
AX ROD T6 50/50 IRR, an amphetamine
“Liq Diane’s Navel”
amphetamine
Dyanavel XR Liquid (d,l‐amphetamine) LiquiXR technology (XR = % IR & % XR not provided by manufacturer/FDA)
The extended‐release component is coated with an aqueous, pH‐ independent polymer
Approved for ages 6 years and older
Dyanavel
“Liq Diane’s Navel”
amphetamine
Dyanavel XR Liquid (d,l‐amphetamine) LiquiXR technology (XR = % IR & % XR not provided by manufacturer/FDA)
The extended‐release component is coated with an aqueous, pH‐ independent polymer
Approved for ages 6 years and older
Dex’s new sandles
Dexedrine Spansules (dextroamphetamine)
pro-drug amphetamine
Spansules = % IR & % XR not provided by manufacturer/FDA
Can sprinkle Spansule‐contents on food
Approved for ages 6 years and older
Also approved for adult Narcolepsy
VYVanse does oral but chews
lisdexamfetamine: pro‐drug of dextroamphetamine) (oral & chewable)
Converted to dextroamphetamine by hydrolytic activity of RBCs
not metabolized by cytochrome P450 enzymes
May empty capsule contents into glass of water/juice or sprinkle contents on food
Approved for ADHD in ages 6 years and older
Also approved for moderate‐to‐severe Binge Eating Disorder in adults
Dexedrine Spansules
Dex’s New Sandles
Dexedrine Spansules (dextroamphetamine)
pro-drug amphetamine
Spansules = % IR & % XR not provided by manufacturer/FDA
Can sprinkle Spansule‐contents on food
Approved for ages 6 years and older
Also approved for adult Narcolepsy
Converted to dextroamphetamine by hydrolytic activity of RBCs
Vyvanse- lisdexamfetamine: pro‐drug of dextroamphetamine) (oral & chewable)
Converted to dextroamphetamine by hydrolytic activity of RBCs
not metabolized by cytochrome P450 enzymes
May empty capsule contents into glass of water/juice or sprinkle contents on food
Approved for ADHD in ages 6 years and older
Also approved for moderate‐to‐severe Binge Eating Disorder in adults
Adderall
Adderall XR (d,l‐ amphetamine/ dextroamphetamine):
only amphetamine that can be given to a child 3 and up
1⁄4 total dose each of 2 salt forms, each of d/l‐amphetamine & dextroamphetamine
XR = 50% IR beads & 50% XR beads
Can sprinkle capsule contents on food
Approved for ages 3 years and older
Also approved for Narcolepsy in adults
My day is 2 salty
Mydayis (l‐amphetamine/dextroamphetamine)
1⁄4 total dose each of 2 salt forms of l‐amphetamine and d‐
amphetamine
33% IR
66% two different pH‐dependent DR beads (33% each)
Can sprinkle capsule contents on food
Approved for ages 13 years and older
oreo has two sides
Concerta- derivative of methylphenidate
(d,l‐methylphenidate)
Phase 1: 22% IR
Phase 2: 78% ER (one hour later, 12 hours total)
OROS® (Osmotic [Controlled] Release Oral [Delivery] System) delivery system with ‘Biphasic’ release property
Approved for ages 6 years and older
ritalin
Ritalin LA (d,l‐methylphenidate)
LA = 50% IR beads + 50% LA beads (enteric‐coated, delayed‐ release)
SODAS® (Spheroidal Oral Drug Absorption System) technology
Can sprinkle capsule contents on food
Approved for ages 6 years and older
Met a date last night
Metadate CD (d,l‐methylphenidate)
CD = beads have
30% IR layer
70% CD layer (release‐control polymers)
May empty capsule‐contents (beads) onto food
Approved for ages 6 years and older
Ap-te si O
Aptensio XR (d,l‐methylphenidate) XR =beads have 40% IR layer & 60% XR layer • Multi‐layer bead‐releasing system Approved for ages 6 years and older May empty capsule contents onto food