ADHD and ASDs Flashcards

1
Q

What is ASD?

A

A lifelong pervasive (home and school) developmental disorder with 2 core symptoms:
1. Persistent deficits in social communication and interaction across multiple contexts
• Social reciprocity – how child responds and reciprocates
• Joint attention – wanting to share an interest
• Non-verbal communications – using or interpreting
• Social relationships – developing and maintaining friends
2. Restricted, repetitive patterns of behaviour, interests, or activities
• Lining up toys, flapping hands, and imitating
• Fixed on certain routines (same school route)
• Restrictive thinking, specific knowledge

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2
Q

When are the symptoms of ASD apparent from and how does it impact life?

A

The symptoms are present from early life but may not become obvious until social demands exceed the capacity of the child. This results in clinically significant impairment in functioning and cannot be attributed to other conditions such as intellectual disability or global developmental delay. Commonly they will have sensory processing issues.

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3
Q

Which genetic conditions is ASD associated with, what is the male:female ratio, how commonly are other siblings affected and what is the most common medical problems associated with it?

A

Definite genetic component particularly fragile X and Rett’s syndrome
If affected sibling, then 5-10% increased risk with next child
Epilepsy associated 30% of the time
4:1 ratio of males to females

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4
Q

Who can make a diagnosis of ASD?

A

Must be made by at least 2 clinicians usually occurring at an MDT meeting including parents, teachers, speech and language therapist, psychiatrist and psychologist.

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5
Q

What are the ICD10 criteria for ASD diagnosis?

A

Before the age of 3 showing impaired or abnormal development in one of the following:
1. Receptive or expressive language as used in social communication
2. Development of selective social attachments or of reciprocal social interaction
3. Functional or symbolic play
After the age of 3 this diagnosis can be confirmed if they have a total of 6 symptoms from 3 categories with at least 2 in the first category and 1 in the other two
1. Impairment of social interaction manifesting as certain symptoms
2. Abnormalities in communication manifesting as certain symptoms
3. Restricted, repetitive, and stereotyped behaviour manifesting as certain symptoms

GARS2 questionnaire for parents and school

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6
Q

How is ASD managed?

A

This is based around support for the child and parents once the diagnosis is made and should be targeted to the patients needs.
Parents should attend training classes and education on ASD as well as being encouraged to claim or apply for disability living allowance.
Direct parents and children to relevant national and local websites and groups.

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7
Q

What drugs can be used for specific symptoms in ASD?

A

There are some drugs that help with specific symptoms
Risperidone for aggression
Melatonin for sleep
SSRIs for repetitive behaviour

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8
Q

What is ADHD?

A

Most common neurodevelopmental disorder of childhood. It has a strong genetic component and has 3 core diagnostic features: impulsivity, inattention, and hyperactivity.

Thought to be due to low levels of dopamine and nor-adrenaline.

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9
Q

Can diagnosis and treatment of ADHD occur before the age of 6?

A

No drugs are licensed until after the age of 6 and diagnosis is difficult before this age.

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10
Q

What differentials should be considered in a child suspected of having ADHD?

A

Hearing impairment, behavioural disorders, age appropriate behaviour and low or high IQ

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11
Q

What problems are associated with ADHD?

A

Self-harm, suicide, learning difficulties (dyslexia etc.) and assault.

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12
Q

How is a diagnosis of ADHD made?

A

This is made using DMS5 criteria
Children up to 16yrs must have at least 6 pervasive Inattention symptoms and/or 6 hyperactivity/impulsivity symptoms, those older than 16 must have 5 and these symptoms must last for 6 months. Can be split into Inattentive or Hyperactive/impulsive subtype.

There must be clear evidence of clinically significant impairment in social, academic, and occupational function.

Can include computer attention test
Education psychology
GARS2 questionnaire for parents and school

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13
Q

How is ADHD managed?

A

Unless the need is immediate treatment should not start and there should be a 10 week watch and wait period.

Behavioural Psychotherapy
Stimulant/Non-stimulant medication

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14
Q

What baseline investigations must be undertaken in children with ADHD prior to commencing treatment?

A

Prior to starting any medication, a baseline ECG, height, weight and BP should be undertaken as most of the medications used are cardiotoxic. These should also be measured at every follow up appointment.

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15
Q

What psychotherapy can be offered to children with ADHD?

A

Behavioural Psychotherapy
Time management and organisational skills as well as parent and teach involvement helping with specific parenting techniques and help in the classroom.

Children may also need help with other issues that medication won’t solve such as anger and aggression issues. Older children often benefit from CBT.

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16
Q

What drugs are used in stimulant medication?

A

First line is Methylphenidate/Dexmethylphenidate (these act as Noradrenaline/dopamine reuptake inhibitors).
Second line is Amphetamines/Dexamphetamine/Lisdexamphetamine

17
Q

What side effects occur as a result of stimulant medication?

A

SE: alopecia, anxiety and depression, decreased appetite, cardiac problems, GI disturbance including dry mouth, cough, headaches and hypertension.

18
Q

When should stimulant medication be given?

A

The time the drug lasts for is important and should be discussed with parents and child. Both types of stimulant work within hours but may take weeks to reach full effect.

Medication should not be given over weekends and holidays as it supresses appetite and may impair growth. Primary stimulant side effects are: agitation, headaches, raised BP and HR and nausea.

19
Q

What drugs are used for non-stimulant medication?

A

Includes: Atomoxetine and Guanfacine (often useful if associated tics). Clonidine can also be trialled. These are 3rd and 4th line medications.

20
Q

What side effects do the non-stimulant medications cause?

A

Side effects primarily focus around: feeling sleepy, headaches, lowering BP and nausea.

21
Q

Do the parents of children diagnosed with ADHD need any kind of help?

A

As well as this, parents should be educated in positive parenting over negative parenting and attend education classes.

22
Q

Should the diet of someone with ADHD even be altered?

A

Normal balanced healthy diet can be consumed unless a specific link has been found between behaviour and food.

23
Q

Are ADHD medications dangerous?

A

Must be careful as the phenidates and amphetamines are controlled drugs and have a high street value. Care must be taken when starting and stopping these drugs due to the issues of withdrawal.