ADHD Flashcards

1
Q

ADHD def’n

A

‘a persistent pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or development…. and negatively impacts directly on social and academic/occupational activities’

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2
Q

GIve 3 adverse outocmes associated with ADHD

A

educational problems (resulting in low rates of high-school graduation and completion of postsecondary education) [6], difficult peer relationships [7] and increased rates of motor vehicle accidents, accidental injuries, and substance misuse

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3
Q

3 RF’s for persistence of ADHD into adulthood

A

combined inattention/hyperactivity, increased symptom severity, comorbid major depressive or other mood disorder, high comorbidity (>3 additional DSM disorders), parental anxiety, and parental antisocial personality disorder [11].

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4
Q

3 RF’s for ADHD

A

in utero exposure to alcohol or tobacco [18] and low birth weight (<2,500 g) [19][20]. Hypoxic–anoxic brain injury [21], epilepsy disorders [22], and traumatic brain injury

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5
Q

5 parts of clinical process in diagnosis of ADHD

A
  • Several visits
  • Detailed history (prenatal, perinatal, medical, mental health)
  • dev/behav hx
  • fam medical and mental health hx
  • review report cards
  • obtain standardized behavioural scales taht eval DSM5

…DON’T Do: lab tests, psych testing

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6
Q

for adhd dx, sx must be present before what age?

A

12

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7
Q

for adhd dx, sx must be present for how long?

A

> 6 mos

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8
Q

5 DDX for ADHD

A
"SLO IT" like SLOW IT DOWN:
Sleep disorder
Learning D/O
ODD
Intellectual disability
Tic D/O
Learning disorder
Sleep disorder
Oppositional defiant disorder
Anxiety disorder
Intellectual disability
Language disorder, mood disorder, tic disorder, conduct disorder
Autism spectrum disorder
Developmental coordination disorder
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9
Q

4 syndromes prevalent in ADHD?

A

Fragile X
Turner
TS
NF1

also 22q11

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10
Q

5 disorders co-morbid with ADHD?

A

CO-AD’S

OCD
*ODD
*CD
bipolar disorder
tic disorders
substance use disorders
*DCD= dev coordination d/o
*Specific learning d/o
*ASD
Eating disroder
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11
Q

3 parts to med exam for ADHD

A

physical, neuro, dysmorpohology assessments

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12
Q

Give 5 non pharm intervention for ADHD

A

DOC’s Do’s:

  • Daily Report Card
  • Organizational skills training
  • Classroom management
  • Social skills training
  • Diet

Also: psychoeducation, exercise, PBT

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13
Q

trial a given stimulant for how long before determining not working?

A

2-4 weeks

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14
Q

two stimulants?

A

dextroamphetamine

methylphenidate

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15
Q

drug holidays in adhd not good for whom?

A

those with risk-taking behaviours or struggling with peer interactions or “at risk for poor outcomes”

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16
Q

which type of stimulant is hardest to take recreationally?

A

extended release

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17
Q

is it ok if adhd patient has appetite suppression at lunch? at dinner?

A

lunch ok; dinner not ok

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18
Q

2 suitable drugs to start for as first chioce older kids iwth adhd?

A

vyvanse (amphetamine/dextroamphetamine);concerta= MPH

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19
Q

2 suitable drugs to start as first choice for younger kids iwth adhd?

A

biphentin (MPH), adderall (dextroamphetamine), vyvanse

20
Q

Which ADHD meds can be given as beads?

A

biphentin, adderall

21
Q

Which ADHD med can be given as powder than can be mixed in liquid or food?

A

vyvanse

22
Q

2 short release ADHD meds?

A

Ritalin SR, Generic MPH ER

23
Q

2 non-stim ADHD meds?

A

atomoxetine Hcl= strattera; intuniv= guanfacine

24
Q

4 side effects of stimulants

A
decreased appetite
"too focused"
irritability
Increased in HR, BP
Raynaud's phenomenon
Psychosis
Delayed puberty
25
Q

who should get ECG before starting ADHD meds?

A

Only children and youth at risk for stimulant-induced cardiovascular AEs (based on family history or a personal history/cardiac examination)

26
Q

do stimulants affect height?

A

can cause decrease in growth but for most kids finally adult height only minnimally affected

27
Q

which non-stim is often used with stims for ADHD?

A

atomoxetine

28
Q

which med is helpful when ADHD patient has oppositional sx?

A

guanfacine

29
Q

Atomoxetine AEs (3)

A

irritability,
headache,
appetite loss,
somnolence

30
Q

Guanfacine AEs:

A

somnolence, syncope, bradycardia

31
Q

guanfactine is what type of drug?

A

Selective alpha 2a-adrenergic receptor agonist

32
Q

what tyep fo drug is atomoxetine = strattera?

A

Selective norepinephrine reuptake inhibitor

33
Q

what type of adhd med requires blood pressure monitorning?

A

guanfacine, clondine (alpha adrenergic drugs)

34
Q

2 reasons for longer half life of atomoxetine in some pts?

A

polymorphism of cytochrome P450; taking other drugs like fluoextine

35
Q

which adhd drugs must be tapered slowly and why?

A

alpha adrenergic drugs; to avoid htn, tachyardia, hypertensive encephalopathy

36
Q

3 syndromes with features of ASD adn ADHD

A

Fragile X
TS
22q11 deletion
Williams

37
Q

2 difficulties of treating pts iwth ADHD + ASD

A
  • Less likely to respond to tx

- More likely to have side effects

38
Q

adhd med helpful in kids iwth ADHD + ASD

A

guanfacine

39
Q

5 conditions associated with ID

A
fragile x
klinefelter
turner
TS
neurofibromatosis
40
Q

pt with adhd and ID: on stimulant. has behavioural sx and doesn’t respond to behavioural interventions. next?

A

risperidone

41
Q

CPS reviews what 3 conditions along with ADHD?

A

ASD, ID, prematurity; these groups have greater impairment

42
Q

what’s the main nonpharm intervention for pts with ADHD + ASD/ID

A

exercise

43
Q

most common comorbidity

A

learning disorder

44
Q

first line tx for preschooler

A

parental behaviour therapy

45
Q

CADDRA contrindication to meds

A

Rule out contraindications to medication:

  1. Glaucoma
  2. Uncontrolled hypertension
  3. Any evidence of significant cardiovascular abnormality