ADHD Flashcards

1
Q

What is ADHD?

A

Attention Deficit Hyperactivity Disorder

It is a co-occurring cluster of impairing symptoms relating to self-regulation (executive functioning)

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2
Q

Diagnostic triad of ADHD?

A
  1. Inattention
  2. Hyperactivity
  3. Impulsivity
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3
Q

Most common ADHD sub-type?

A

Combined type ADHD, AKA hyperkinetic disorder

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4
Q

Features of combined type ADHD?

A
Triad of difficulties and are:
• Developmentally inappropriate
• Impairing
• Pervasive (present in all aspects of life and in all environments, e.g: home, school, etc)
• Longstanding
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5
Q

What type of disorder is ADHD?

A

Spectrum disorder - there is a symptom cluster on a continuum in the general population

Cut-off is based on impairment, clinical judgement, score on rating scales, etc

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6
Q

Impact of the core symptoms of ADHD?

A

In home / community:
• These kids are complicated to their parents and family stress levels are high (viewed as a family burden)
• Increased anger and upset
• Increased risk of harm, e.g: due to impulsive behaviour

School:
• It is a barrier to learning
• Tend to be in trouble frequently
• Disorganised, forgetful and often lose belongings

Impact on self-worth, interpersonal and social connections

Increased RTAs, other accidents, etc

School and occupation suffer

Higher divorce rate and increased risk of early parenthood

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7
Q

Co-morbid symptoms that commonly occur alongside ADHD?

A
  • Co-morbid disorder symptoms
  • Hyperactive symptoms
  • Inattentive symptoms
  • Impulsivity symptoms
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8
Q

Co-morbid difficulties that arise with ADHD?

A

Social communication difficulties

Learning Disability (LD)

Attachment difficulties, e.g: parents and friends often find it difficult to bond with these complex children

Mood and anxiety problems

Behavioural disorders - when these arise in children, it is almost universally assoc. with ADHD:
• Oppositional Defiant Disorder (ODD)
• Conduct Disorder (CD)

Substance misuse

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9
Q

Outcome of ADHD in adults?

A

High rates of crime, substance misuse and psychiatric disorder

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10
Q

Occurrence of ADHD?

A

5% worldwide (although this likely is only the case when the diagnostic criteria are broader)

i.e: common; however, it is still under-diagnosed

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11
Q

Cause of ADHD?

A

There are genetic, environmental and neurobiological risk factors, e.g: peri-natal insults

Genetic risk is an important precursor but this may be compounded/turned on by 1 of several environmental risk factors, which may be antenatal; these causal factors results in structural & functional differences across several regions / networks

Environmental factors affect ADHD at every level of development:
• Genes 
• Brain structure and function
• Cognition
• Symptoms
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12
Q

Effect of ADHD on memory?

A

Assoc. with significant deficits in both executive and non-executive aspects of working memory

NOTE - working memory in children with ADHD resembles that of patients with Alzheimer’s disease

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13
Q

Imporant information to collect and use to make a diagnosis of ADHD?

A

Parent and school reports

Screening questionnaires:
• SDQ
• DAWBA

Structured diagnostic questionnaires:
• Conners Rating Scale
• ADHD rating scale
• SNAP IV

Background info regarding risk

Careful review of co-morbidities

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14
Q

Background risk factors for ADHD?

A

FH

Male gender

SE status (difficult to determine, as SE status may contribute to ADHD or ADHD could result in low SE status)

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15
Q

Examinations that can be carried out

A

School observation

Observation in clinic room

Potentially cognitive assessment

NOTE - these are not always helpful

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16
Q

Prognosis of ADHD?

A

Symptoms commonly persist throughout childhood and core symptoms may persist into adulthood

However, the manifestation of symptoms may change according to development stage (and gender); some will ‘grow out’ of ADHD, as part of the brain’s natural developmental process

17
Q

Psychological therapies used for ADHD?

A

1st line:
• Parent training with the new forest parenting programme (8 weeks)
• Behavioural classroom management strategies

2nd line:
• Social skills training
• Sleep and diet - there is evidence that certain dietary factors, e.g: sugary foods, can trigger/exacerbate symptoms; there is little evidence that increasing sleep improves ADHD

18
Q

Pharmacological treatments used for ADHD?

A

1st line (‘stimulants’):
• Methylphenidate (RITALIN)
• Dexamfetamine
• Lisdexamfetamine

2nd line - atomoxetine

3rd line:
• Anti-depressants
• Anti-hypertensives
• Anti-psychotics

19
Q

Efficacy of psychological therapies?

A

Important and may address co-morbid or secondary difficulties at home; also allow for a better understanding of the child at home and at school

However, it may not be sufficient in severe, impairing cases

20
Q

Mechanism of action of ‘stimulants’ used in ADHD?

A

Improve dopaminergic neurotransmission in networks inv. in executive functioning, inc. in the pre-frontal cortex

This directly improves core symptoms

21
Q

Side effects of ‘stimulants’?

A

Usually minor, e.g: appetite and sleep reduction

Dysphoria (profound state of unease or dissatisfaction), anxiety and tics may occur

22
Q

Examples of non-stimulants available for ADHD and their mechanism of action?

A

Atomoxetine - noradrenergic and dopaminergic agonist

Guanfacine - an α2-agonist; has effects on the pre-frontal cortex, for ADHD control

23
Q

Efficacy of pharmacological therapies for ADHD?

A

Very effective