ADHD

Question 1

Dexamphetamine

Answer 1

A) CNS Psychostimulant

B)

1. ADHD
2. Narcolepsy

C)
2.5 - 60 mg (divided doses)

D)
1. Heart Rate (increase - can worsen cardiac conditions)
2. BP (increase)
3. PSYCH and MOOD destabilisation (worsen or provoke aggression and agitation)
4. Drug MISUSE and DIVERSION**
5. Development or Worsening of TICS**
6. HEIGHT and WEIGHT in children (reduced growth)**
NO renal or hepatic

E)
Labels: 5, 12
#Avoid taking doses after EARLY AFTERNOON if you have trouble sleeping at night
S/E
*GIT (nausea, diarrhoea, loss of appetite, weight loss)
*CNS (anxiety, irritability, insomnia, headache, dizziness, aggression)
*HEART (tachycardia, palpitations, changes in BP)

Question 2

Lisdexamfetamine (Vyvanse)

Answer 2

A) CNS Psychostimulant

B)
1. ADHD

C)
30-70 mg ONCE daily

D)
1. Heart Rate (increase - can worsen cardiac conditions)
2. BP (increase)
3. PSYCH and MOOD destabilisation (worsen or provoke aggression and agitation)
4. Drug MISUSE and DIVERSION**
5. Development or Worsening of TICS**
6. HEIGHT and WEIGHT in children (reduced growth)**
NO renal or hepatic

E)
Labels: 5, 12
#Avoid taking doses after EARLY AFTERNOON if you have trouble sleeping at night
S/E
*GIT (nausea, diarrhoea, loss of appetite, weight loss)
*CNS (anxiety, irritability, insomnia, headache, dizziness, aggression)
*HEART (tachycardia, palpitations, changes in BP)

Question 3

Methylphenidate (Ritalin or Concerta)

Answer 3

A) CNS Psychostimulant

B)

1. ADHD
2. Narcolepsy

C)
Ritalin: 10-60 mg daily (2-3 doses)
Ritalin LA: 10-80 mg MANE
Concerta: 18-72 mg MANE

D)

1. Heart Rate (increase - can worsen cardiac conditions)
2. BP (increase)
3. PSYCH and MOOD destabilisation (worsen or provoke aggression and agitation)
4. Drug MISUSE and DIVERSION**
5. Development or Worsening of TICS**
6. HEIGHT and WEIGHT in children (reduced growth)**
7. HEPATIC** (halve dose)

E)
Labels: 5, 12, A* (controlled release)
#Avoid taking doses after EARLY AFTERNOON if you have trouble sleeping at night
S/E
*GIT (nausea, diarrhoea, loss of appetite, weight loss)
*CNS (anxiety, irritability, insomnia, headache, dizziness, aggression)
*HEART (tachycardia, palpitations, changes in BP)

Question 4

Atomoxetine (Strattera)

Answer 4

A) Noradrenaline Re-uptake Inhibitor

B)
1. ADHD

C)
0.5 mg/kg - 1.4 mg/kg (1 or 2 doses)
MAX: 100 mg daily

D)
1. BP (increase)
2. Heart Rate (increase)
3. ECG (rare- prolonged QT)
4. SUICIDAL thoughts or behaviour
5. Drug INTERACTIONS (CYP2D6 substrate)
6. HEPATIC (hepatic dysfunction)
NO renal

E)
Labels: 5, 12+, A
#Takes 2-4 weeks before symptoms start to improve
#Taking it AFTER FOOD may help to reduce nausea
**DR - (hepatic dysfunction) - unusual tiredness, loss of appetite, yellowing of the skin or eyes, dark urine, pale faeces
S/E
*GIT (nausea and vomiting, abdo pain, dyspepsia, decreased appetite)
*ANTICHOL (dry mouth, mydriasis)
*CARDIAC (palpitations
*CNS (dizziness, irritability, aggression, temper tantrums)