ADH 3; Dysrythmias,Rx anti-anginals/lipidemics/dysrhythmias Flashcards
What do Nitrates do?
VASODILATION; relax smooth muscles in blood vessles; BP
decrease afterload (diastolic)
decrease preload/resistance (systolic)
Nitrates; PT teaching for…
Sublingual
Transdermal
PO
Sublingual - should fizzle/tingle, if inactive, new prescription
Transdermal - gloves* take off oldpatch, rotate sites, plain skin (no hair/scars) ON/OFF 12 hrs
PO - take on an empty stomach
Nitrates; WWND??
check BP
watch for O/H
HOLD if systolic is below 100; document & call Dr
head aches; admin NSAIDS - Aspirin or Analgesic - Tylenol
Nitrates; avoid…
NO ETOH or Viagra!!!
What do Calcium Channel Blockers do??
3
DEC intracellular calcium & promotes VASODILATION
DEC afterload/workload ofheart
CCB; WWND?? check/monitor
check BP, HR, RR, lung sounds
Monitor EKG
check bowels
CCB; may…
CCB WILL NOT
WORSEN contractions causing HF/arrythmias
cause CONSTIPATION
WILL NOT RELIEVE AN ACUTE ATTACK
CCB; Cardizem is to manage what arrythmias? 4
slows heart
S-Tach
SVT
A-Fib
A-Flutter
What do Beta Blockers do??
Block SNS/vasoconstriction
to DEC cardiac workload
SLOW HR
DEC contractions
DEC O2 requirements
WILL NOT PREVENT AN ACUTE ATTACK; need Nitroglycerine
Beta Blockers; given for…
& what arrythmias? 4
Angina, Hypertension
prevents SVT, V-fib
also for A-fib, A-flutter
Beta Blockers; WWND??
check HR, RR, O2; X asthma, COPD
BP (hold if under 50)
BG (mask hypoglycemia)
BB; (loPRESSor) Lopressor controls…
how would you admin??
controls ventricle rate
5mg IV push
Reductase Inhibitors/Statins; WDTD?
Drugs
block enzymes HMG-CoA; lowers cholesterols
ZOCOR
Reductase/Statins; Monitor…
LFTs (activates in liver) Muscle weakness/CRAMPS/Rhabdomyolysis CPK levels (tissue injury)
Reductase/Statins; PT teaching & Drug Interactions
Take in evening (when you make lipids)
Avoid ETOH
D/I: erythromyocin (abx for skin/acne), grapefruit juice - inc risk of myopathy
Bile Acid Sequestrants; Questran
WDTD?
Bind with bile acids in interstitial lumen to lower LDL
Bile Acid Sequestrants;Questran
PT teaching - drug interactions
THERE ARE A LOT!! decreases absorption of other medications, TAKE 1 HR BEFORE or 4-6 HRS AFTER
Bile Acid Sequestrants;Questran
preparation/WWND?
Mix powder with 120-180 ml of any liquid
Monitor bowel function; can cause constipation
Cholesterol Absorption Inhibitors; Zetia
WDTD?
Inhibit absorption of CHL from small intestine
DEC total serum CHL
Niacin Vit B3 (OTC); must be taken in HIGH doses
Inhibits release of free fatty acids
Removes triglycerides
DEC LDL
Niacin Vit B3 (OTC); Monitor
LFTs; may cause liver insufficiency
INC in uric acid levels
FLUSHING; Aspirin, Ibuprofen
CLASS 1
CLASS 2
CLASS 3
CLASS 4
CLASS 1 - Sodium channel blockers
CLASS 2 - Beta blockers
CLASS 3 - Potassium channel blockers
CLASS 4 - Calcium channel blockers
CLASS 1 Sodium channel blockers; work by
blocking the sodium channels in the cell membrane during an action potential
CLASS 2 Beta blockers; work by
causing depression of phase 4 of action potential
CLASS 3 Potassium channel blocker; work by
prolonging phase 3 of action potential
Class 4 Calcium channel blockers
in membrane
CLASS 1
DEC conduction & velocity; slow impulses in atria & ventricle
SUPPRESS automaticity
INC recovery time
CLASS 1
A.
B.
C.
CLASS 1
A. Quinidine
B. Lidocaine
C. Rythmol
CLASS 1 A - Quinidine
used for what arrhythmia?
PAC/PVC
A-Fib
V-Tach
CLASS 1 A - Quinidine
LEVELS?
TOXICITY? s/s
(2 - 5mcg/ml) TOXICITY S/S -visual disturbances -headache -dizzy -widening QRS -arrhythmias, ectopic beats (SVT) -30 - 35% diarrhea, stomach cramping
CLASS 1 A - Quinidine
WWND? PT teaching?
Take apical rate
Monitor EKG
PT- avoid ant acids; needs acidic environment
CLASS 1 B.- Lidocaine…MGMT of??
MGMT of acute ventricle arrhythmias
PVC
V-Tach - w/pulse
prevents V-Fib
CLASS 1 B.- Lidocaine
LEVELS?
WWND?
1.5 - 6mcg/ml
Monitor for CNS symptoms; dizzy, slurred speech
Seizure precautions!
CLASS 1 C - Rhythmol PO…works by??
MGMT of??
“you’re tachy & i hate you” - School of Rhythmol
prolonging AV node refractory period
life threatening ventricular arrythmias (tachydysrythmias)
also A-Fib/A-Flutter
CLASS 2 Beta Blockers
Slows SNS
DEC SA node activity
Eliminate/DEC atrial ectopicfoci stimulation
DEC ventricular contraction
CLASS 2 Beta Blockers; Lopressor..controls?
DOSE
controls ventricular rate of A-fib/A-flutter
5mg IV push
CLASS 3 Potassium channel blockers
- blocks potassium channels in purkinje fibers & ventricular muscle
- prolongs refractory period/delay repolarization
CLASS 3 Potassium channel blockers:
Amiodarone IV/drip for the DEAD, Amidead?
Drug of choice for treating V-fib (dead) & pulseless V-tach (dead)
CLASS 3 Potassium channel blockers: Amiodaron Nx implementations (7) Rx, L-T-P-N-E
Respiratory toxicity; pulmonary fibrosis - assess for cough/SOB,routine CXR Coumadin Digoxin toxicity LFT Hyper/Hypo Thyroid Neuro effects Photosensitivity Eye exams/EKG
CLASS 4 Calcium channel blockers
blocks influx of calcium into the SA & AB nodes
slows conduction
DEC ventricular response to rapid A-Fib/A-Flutter
ALT to Adenosine for PSVT
CLASS 4 Calcium channel blockers
Cardizem
DOSE (2)
WWND?
Controls ventricular reate in A-fib/A-flutter
25mgIV bolus OR 5-15mg/hr drip
Monitor rate, rhythm
Adenosine
given for?
works by?
admin?
acute treatment of PSVT
slows electro-conduction though AV node
short acting - rapid IV push, 6mg, 6mg, 12mg
Atropine Sulfate
given for?
Bradycardia; HR <60 w/dizziness, groggy, pale
IV push: 0.5 - 1 IV every 3 - 5min
Magnesium Sulfate
Torsades de pointes
IV push: 1 - 2 gm over 2min