Adenomyosis Flashcards
What is adenomyosis
Adenomyosis is characterized by the presence of endometrial tissue within the myometrium.
Who is it more common in
It is more common in multiparous women towards the end of their reproductive years.
What are the features
dysmenorrhoea
menorrhagia
enlarged, boggy uterus
What is the investigation of choice
MRI is the investigation of choice
What is the symptomatic treatment
Tranexamic acid for menhorrhagia
What are the other non symptomatic treatments
GnRH agonists
uterine artery embolisation
hysterectomy
What is the mechanism of action of Tranexamic acid
Synthetic analogue of lysine - anti fibrinolytic by reversibly binding four to five lysine receptor sites on plasminogen. This decreases the conversion of plasminogen to plasmin, preventing fibrin degradation and preserving the framework of fibrin’s matrix structure
