Additions Flashcards
What is the effect of hyperkalemia on membrane potential?
i) Mild hyperkalemia: decrease K efflux → decrease the negativity of RMP i.e. less than - 70 mV (e.g. – 60 mV)→↑ excitability of nerve fibers
ii) Marked hyperkalemia: make the resting membrane potential to be more negative → inactivation of Na channels by h gates which close within 0.5 -1.0 m.sec of opening of m gate → decrease membrane excitability
What is the number of neurons?
1 trillion
What is the function of neuroglia?
Support & protect neurons.
What is the number of neuroglia?
10: 50 times more than neuron
CHARACTERISTICS of interneurons
Small size. Inside CNS. 99% of neurons. Integrative function Connect afferents with efferents.
What are the characters of the cell body?
Enlarged part of the nerve that contains Contain nucleus, microfilament, and microtubule.
Control metabolism and nutrition of nerve fibers.
What is a collection of cell bodies called?
Collection of cell bodies inside CNS called: centre = synapse = nucleus
Collection of cell bodies outside CNS called: ganglia.
What are the cell processes?
a) Axon (axis cylinder).
b) Dendrites.
What are the characters of myelin or medullary sheath?
Lipoprotein complex.
Electric insulator.
White in color
Envelop all axon except axon terminal and nodes of ranvier
Interrupted at every (.1-1mm) which is the site of exchange of ions and water.
What are the characters of Schwan or cellular sheath?
Not found inside CNS.
Glia like.
Its outer layer is called neurolemma.
Regenerate damaged nerve fiber by the formation of the myelin sheath, only outside CNS.
What is the nerve trunk formed from?
Formed of multiple nerve fibers.
Bundles of nerve fibers are surrounded by perineurium
Inside the bundles: each nerve fiber is surrounded by endoneurium.
The nerve is surrounded by loose connective tissue called epineurium and supplied by blood vessels.
What is the function of the nerve trunk?
a) Sensory nerve: carry sensation from receptor to CNS.
b) Motor nerve: carry motor orders from CNS to the effector organ.