Additions Flashcards

1
Q

What is the effect of hyperkalemia on membrane potential?

A

i) Mild hyperkalemia: decrease K efflux → decrease the negativity of RMP i.e. less than - 70 mV (e.g. – 60 mV)→↑ excitability of nerve fibers
ii) Marked hyperkalemia: make the resting membrane potential to be more negative → inactivation of Na channels by h gates which close within 0.5 -1.0 m.sec of opening of m gate → decrease membrane excitability

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2
Q

What is the number of neurons?

A

1 trillion

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3
Q

What is the function of neuroglia?

A

Support & protect neurons.

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4
Q

What is the number of neuroglia?

A

10: 50 times more than neuron

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5
Q

CHARACTERISTICS of interneurons

A
 Small size.
 Inside CNS.
 99% of neurons. 
 Integrative function
 Connect afferents with efferents.
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6
Q

What are the characters of the cell body?

A

 Enlarged part of the nerve that contains Contain nucleus, microfilament, and microtubule.
 Control metabolism and nutrition of nerve fibers.

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7
Q

What is a collection of cell bodies called?

A

 Collection of cell bodies inside CNS called: centre = synapse = nucleus
 Collection of cell bodies outside CNS called: ganglia.

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8
Q

What are the cell processes?

A

a) Axon (axis cylinder).

b) Dendrites.

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9
Q

What are the characters of myelin or medullary sheath?

A

 Lipoprotein complex.
 Electric insulator.
 White in color
 Envelop all axon except axon terminal and nodes of ranvier
 Interrupted at every (.1-1mm) which is the site of exchange of ions and water.

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10
Q

What are the characters of Schwan or cellular sheath?

A

 Not found inside CNS.
 Glia like.
 Its outer layer is called neurolemma.
 Regenerate damaged nerve fiber by the formation of the myelin sheath, only outside CNS.

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11
Q

What is the nerve trunk formed from?

A

 Formed of multiple nerve fibers.
 Bundles of nerve fibers are surrounded by perineurium
 Inside the bundles: each nerve fiber is surrounded by endoneurium.
 The nerve is surrounded by loose connective tissue called epineurium and supplied by blood vessels.

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12
Q

What is the function of the nerve trunk?

A

a) Sensory nerve: carry sensation from receptor to CNS.

b) Motor nerve: carry motor orders from CNS to the effector organ.

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