Addison Disease Flashcards

1
Q

What happens in Addison disease (hormone) ?

A

Adrenocortical insufficiency from lack of ATCH

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2
Q

Addis disease

4 chronic causes
3 acute

A

Autoimmune, idiopathic, histoplasmosis, TB

Sudden D.C. Steroid, infection or remove adrenal glands

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3
Q

Disease vs crisis s/s?

A

Disease develops slow

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4
Q

Signs and symptoms add disease 5

Look like and lab

A
Fatigue
Hyper pigmentation 
Changes in mental- depression 
Dehydration- loss na and water 
BP- hypotension
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5
Q

Diagnosis of add disease/ crisis
7
labs , test

A
Adrenocortical- serum levels in AM 
BG less than 50 
NA less 130
K- more 5 
Bun/creatinine/hct
Chloride less than 90 
WBC- elevated
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6
Q

Treatment of Addison

4 donts results in what 2

A

Overexertion, exposure cold, acute infection,decrease salt intake lead to shock or death

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7
Q

Treatment of Addison
5
meds/care

A
Abtx if infected 
Increase PO NA intaks 
Life long replacement 
Total rest- non stress 
Monitor cardiac and fluid balance
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8
Q

Hormone replacement

When to increase 4

A

Stress
Infection
Trauma /surg
Emotional upset

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9
Q

Food give in add crisis 4

A

Na/sugar

Gatorade, tomato soup, bouillon cubes
No high in caffeine

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10
Q

Adrenals crisis 6 causes

A
Infection 
Trauma 
Na loss 
Hyper hydrosis 
Over exertion 
Cold exposure
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11
Q

Signs and symptoms 6 Addison crisis

Look like feel like

A
Cyanosis or pallor 
Fever 
Increase P and RR
Decrease BP
Confusion 
Abd pain
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12
Q

Treatment 4 add crisis

Types fluids/care

A

Ivf- glucose and NA bolus at first

Iv corticosteroid- life steroid replacement

Vasopressin

No activity-recumbent

Incr- Na when stress or hot

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13
Q

Cushing syndrome what happens
? Hormone
Who it effects

A

Too much ACTH- pretezone

In women too much make sex hormone men- man boobs

20-40 women 5x likely

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14
Q

What Cushing syndrome (signs) look like? 7

A
Obesity- HTN CHF 
Thing hair 
Thin extremities 
Buffalo jump 
Moon face 
Hirsutism
No menses
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15
Q

Cushings

Symptoms- feel 4

A

Weak
Sleep disturbance
Glucose intolerance
Slow wound healing

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16
Q

Diagnosis of cushings disease 4

Labs and test

A

Increase na and BG
Decrease k

Dexamethosone - 1gm at 11p then cortisol level 8am cortisol higher than 5 abnormal

17
Q

Treatment of cushings 5

Surgery/procedure/monitor

A

Decrease amt steroid

Transpheniod hypophysectomy/ adrenalectomy

Radiate pituitary gland
Avd injury encourage test
Monitor for crisis