Addiction: Describing and Developing Addiction Flashcards

Describing addiction: physical and psychological dependence, tolerance and withdrawal syndrome. Risk factors in the development of addiction, including genetic vulnerability, stress, personality, family influences and peers.

1
Q

What is an addiction?

A

A disorder where an individual takes a substance or engages in a behaviour that is pleasurable but eventually becomes compulsive with harmful consequences.

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2
Q

What is physical dependence?

A

A state of the body due to habitual substance abuse which results in a withdrawl syndrome when the drug is reduced or stopped.

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3
Q

What is psychological dependence?

A

A compulsion to continue taking a substance or performing a behaviour because its use is rewarding.

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4
Q

What is tolerance?

A

A reduction in response to a substance, so that an addicted individual needs more to get the same effect.

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5
Q

What is withdrawl syndrome?

A

A set of symptoms that develop when an addicted person abstains from or reduces their substance abuse.

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6
Q

What are risk factors?

A

Any internal or external influence that increases the likelihood a person will start using addictive substances or engage with addictive behaviours.

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7
Q

Explain behavioural tolerance:

A

When an individual learns through experience to adjust their behaviour to compensate for the effects of a substance.

e.g. people addicted to alcohol learn to walk more slowly when they are drunk to avoid falling over.

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8
Q

Explain cross-tolerance:

A

When developing tolerance to one type of substance can reduce sensitivity to another type.

e.g. Those who have developed a tolerance to the sleep-inducing effects of alcohol need higher doses of anaesthetic.

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9
Q

What are the two main types of tolerance?

A

Behavioural tolerance
Cross-tolerance

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10
Q

How can cross-tolerance be used theraputically?

A

The unintentionally addicted substance can be given in place of the addicted substance.

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11
Q

What are the 5 risk factors for developing an addiction?

A
  • Genetic vulnerability
  • Stress
  • Personality
  • Family influences
  • Peers
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12
Q

Explain genetic vulnerability as a risk factor for developing an addiction:

A
  • People do not inherit an addiction itself, but instead a predisposition to dependence.
  • Genes may determine the activity of neurotransmitter systems (e.g. dopamine) in the brain; affecting behaviours like impulsivity that predisposes someone to dependence.
  • Kendler looked at adults who had been adopted as children from families where at least one biological parent had an addiction.
  • They found that these children had a significantly greater risk of developing an addiction, compared to adopted children with no family history of addiction
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13
Q

Explain stress as a risk factor for developing an addiction:

A
  • People who experience stress may turn to drugs as a form of self- medication (e.g. to avoid pain or feel pleasure)
  • Stress can include both present and previous experiences.
  • Epstein found a strong correlation between childhood rape and alcohol addiction- but only for women diagnosed with PTSD.
  • Addiction is not an inevitable response to rape but early stressful events may lead to a vulnerability.
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14
Q

Explain personality as a risk factor for developing an addiction:

A
  • Individual personality traits such as hostility and neuroticism may increase the risk of addiction.
  • Although there is no such thing as an ‘addictive personality’.
  • Bahlmann interviewed 55 alcohol-dependent people, with 18 of them having APD.
  • Found that APD developed on average 4 years before their alcohol dependence. APD is a risk factor for alcohol addiction
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15
Q

Explain family influences as a risk factor for developing an addiction:

A
  • Living in a family which uses addictive substances and/or has positive attitudes about addictions increases a person’s likelihood of developing an addiction
  • Livingston et al found that final year high-school students who were allowed to drink alcohol at home were significantly more likely to drink excessively at college.
  • This is likely because they have the approval from their parents, and so are more likely to conduct this behaviour.
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16
Q

Explain peers as a risk factor for developing an addiction:

A
  • As children age, peer relationships become the most important risk factor for addiction.
  • Even when an adolescent’s peers have not used drugs themselves, their attitudes towards drugs may still be influential.
  • O’Connell et al found that there were 3 major elements to peer influence as a risk factor: Attitudes and norms, opportunities, overestimating how much their peers are drinking.
17
Q

The existence of withdrawl syndrome indicates that a ______ _______ has developed.

A

Physical dependence

18
Q

Why do withdrawl symptoms usually encourage the relapse of an addiction?

A
  • The withdrawal symptoms are unpleasant and cause discomfort.
  • Motivates individuals to relapse to avoid withdrawal symptoms
19
Q

Withdrawal typically has two phases: the _____ withdrawl phase, and the ____ withdrawl phase.

A

Acute
Prolonged

20
Q

What is the acute withdrawal phase?

A
  • Begins within hours of abstaining from substance/behaviour.
  • Features intense cravings for the substance (reflecting a strong physical and psychological dependence)
  • Symptoms gradually decrease, usually over days.
21
Q

What is the prolonged withdrawl phase?

A
  • Symptoms that continue for extended periods of time (e.g. months, years).
  • Individuals become highly sensitive to cues they associate with the substance (e.g. rituals, location, items).
  • Significantly increases relapse rate.
22
Q

What are the 3 evaluation points for risk factors:

A
  • Control of genes (S)
  • Real world application (S)
  • Interaction between factors (L)
  • Methodological issues (L)
23
Q

Explain control of genes (S) as an evaluation point for risk factors:

A
  • Looking at risk factors together means you can identify interactions between genes
  • Most factors are an immediate influence on addiction, but how we respond to the stress and to the extent to which we seek thrill are both partly genetic.
  • Genetic vulnerability may be the most significant risk factor as it has the ultimate influence on others.
24
Q

Explain real world application (S) as an evaluation point for risk factors:

A
  • Some researchers believe that focusing on risk factors is an effective way of preventing and treating addictions.
  • If we know what the risk factors are then we can identify those at risk and try to work on prevention.
25
Q

Explain interaction between factors (L) as an evaluation point for risk factors:

A
  • Having individual risk factors means that we ignore the effect of interactions and the positive effect that some may have.
  • Combinations of risk factors matter more than individual factors.
  • Multiple risk factors can cause an increased likelihood of developing an addiction e.g. a genetic predisposition to nicotine alongside parents who smoke.
    -However can also decrease the likelihood of developing an addiction e.g. greater parental monitoring and lower levels of impulsivity.
26
Q

Explain methodological issues (L) as an evaluation point for risk factors:

A
  • Correlation does not imply causation
  • Many of the studies in this area find a correlation between risk factors and addiction e.g. extreme stress and addiction are found to be strongly correlated.
  • However does not mean that risk factors cause addiction.
27
Q

What are the two main mechanisms that create a genetic vulnerability to addiction?

A
  • Number of dopamine (D2) receptors
  • Ability of nicotine enzymes (CYP2A6)
28
Q

Explain how an individual’s number of D2 receptors can increase their genetic vulnerability to addiction?

A
  • The number of D2 receptors we have is genetically controlled.
  • People that have addictions have been found to have an abnormally low number of D2 receptors.
  • Fewer receptors means less dopamine activity, so using drugs is a way to compensate for this deficiency.
29
Q

Explain how an individual’s ability of nicotine enzymes can increase their genetic vulnerability to addiction

A
  • Some individuals are more able to metabolise certain substances and this is linked to addiction.
  • Pianezza et al found that some people lack a fully functioning enzyme (CYP2A6) which metabolises nicotine.
  • They also smoke significantly less than smokers with the fully functioning version.
30
Q

Abnormally functioning CYP2A6 enzymes mean an individual is ____ likely to become addicted to nicotine.