Addiction And Substance Misuse Flashcards
Opioids include…
Heroin, morphine, codeine, fentanyl, oxycodone, hydromorphine
Opioid receptors
Mu, delta, kappa
Opiold appearance and behavior
Appearance- Pinpoint pupils, decrease breathing rate (below 12 breaths/min) decreased pulse, decreased temp
Behavlor.- lethargy, Somnolence (falling asleep frequently), Slurred speech, euphoria, psychomotor retardation
CNS depressants agonize ___________ activity
GABA
Ventral segmental area
The center of dopamine release
Amygdala
Emotions “I love this feeling”
Nucleus accumbens
Motor: moves towards the drug
Prefrontal cortex
Focuses on the drug
Hippocampus
Memories: remember all aspects of the experience
Goals of treating a person with addiction issues
Withdrawal - Safely and comfortably withdrawing from drug Use
Maintenance- helping the person stay abstinent from drugs
Most common antidote for opioid overdose
Naloxone (narcan)
Naltrexone
Opioid antagonist
Blocks opioid use reward
Buprenorphine
Harm reduction
Partial agonist for opioid receptors (gives plateau effect)
Methadone
Opioid analgesic
Clonidine
Helps with cardiac symptoms of withdrawal
Benzodiazepines
Detox from chronic alcohol use
Propranolol
Used for cardiovascular effects of withdrawal
Metabolized by liver
Disulfiram
Causes serious illness when one tries to drinks
Operant conditioning of punishment
Monitor live functioning for first 14 days then periodically after
Nicotine increases ____________ and ________________
Heart rate and blood pressure
Bupropion
NDRI
Varenicline
Nicotine partial agonist
Leads to decrease desire to smoke
