ADCs Flashcards
1
Q
Brentuximab vedotin
A
Brand: Adcetris Target: CD30 Payload: MMAE Discovery: Seattle Genetics Type: human-mouse chimeric Date: 2011
Indication: Hodgkin lymphoma and systemic anaplastic large cell lymphoma.
PK: MMAE causes cell cycle arrest by disruption of the cytosolic mictrotuble network.
