Adaptive Immunity Flashcards
1
Q
Describe Adaptive Immunity
A
- Slow onset/response
- Antigen specific
2
Q
Types of Lymphocytes Involved in Adaptive Immunity
A
- B Cell
- Helper T Cell
- Cytotoxic T Cell
- Regulatory T Cell
3
Q
Naive T Cell vs. Effector T Cell
A
Naive:
- Likely to be in peripheral blood, lymph
- NO EFFECTOR FUNCTION
Effector T Cell
- Likely to be in inflamed/injured tissues
- Cytokine secretion (CD4)
- Cytotoxic Activity (CD8)
4
Q
Naive B Cell vs. Effector B Cell
A
Naive:
- In membrane form of IgM/IgD
- NO EFFECTOR FUNCTION
Effector B Cell
- Antibody secretion (plasma cell)
- Class switching to IgG, IgA, or IgE
5
Q
Effector Functions of IgG
A
- Complement Activation
- Opsonization
- Antibody-Dependent NK Cytotoxicity
- Neonatal Immunity
- Microbe Neutralization
- Has the highest serum concentration
- Has the longest half life
6
Q
Effector Functions of IgM
A
- In Naive B Cell
- Complement Activation
7
Q
Effector Functions of IgA
A
- Provides Mucosal Immunity
8
Q
Effector Functions of IgE
A
- Defend against helminthic infection
- Activation of allergies (mast cell degranulation)
- Has the lowest serum concentration
- Has the shortest half life
9
Q
Another Name for CD4 T Cell
A
Helper T Cell
10
Q
Another Name for CD 8 T Cell
A
Cytotoxic T Cell
