Adaptive Immunity Flashcards
Antigen
Foreign substance that comes into the body that are either recognized or not recognized
Antibodies
Protein that binds to antigens so they can be remembered in the future
Clonal diversity
Production of large numbers of B and T cells
IgG
Most abundant immunoglobulin
The most protective activity against infection
Major class found in the blood of the fetus
IgE
Protects from infection with large parasites
Initiates inflammatory reaction to attract eosinophils to the site of infection
Causes anaphylaxis
IgA
The dominant secretory immunoglobulin
Prevents attachment and invasion of pathogens through mucosal membranes.
Hypersensitivity
Inflated immune response to a foreign substance
Autoimmunity
Mistakes self as non-self
Alloimmunity
Inadequate immune reaction to members of the same species
B cells
Produced in bone marrow
Enters blood and reacts with the antigen
Cytotoxic T cells
Attack the antigen directly
IgM
The largest immunoglobulin
The first produced in the primary response to antigens
Catecholamines
Hormones released from adrenal medulla during the stress response activating the sympathetic nervous system
Norepinephrine
Epinephrine
Cortisol
Hormones released from adrenal cortex in the stress response
Type 1 IgE Mediated Hypersensitivity
Immediate
Local or systemic
Allergen activates IgE when binds to mast cells
At next exposure, the antigen binds with the surface IgE, releasing mediators and triggering the complement system