Adaptive Immunity Flashcards

1
Q

Antigen

A

Foreign substance that comes into the body that are either recognized or not recognized

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2
Q

Antibodies

A

Protein that binds to antigens so they can be remembered in the future

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3
Q

Clonal diversity

A

Production of large numbers of B and T cells

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4
Q

IgG

A

Most abundant immunoglobulin
The most protective activity against infection
Major class found in the blood of the fetus

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5
Q

IgE

A

Protects from infection with large parasites
Initiates inflammatory reaction to attract eosinophils to the site of infection
Causes anaphylaxis

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6
Q

IgA

A

The dominant secretory immunoglobulin

Prevents attachment and invasion of pathogens through mucosal membranes.

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7
Q

Hypersensitivity

A

Inflated immune response to a foreign substance

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8
Q

Autoimmunity

A

Mistakes self as non-self

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9
Q

Alloimmunity

A

Inadequate immune reaction to members of the same species

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10
Q

B cells

A

Produced in bone marrow

Enters blood and reacts with the antigen

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11
Q

Cytotoxic T cells

A

Attack the antigen directly

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12
Q

IgM

A

The largest immunoglobulin

The first produced in the primary response to antigens

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13
Q

Catecholamines

A

Hormones released from adrenal medulla during the stress response activating the sympathetic nervous system
Norepinephrine
Epinephrine

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14
Q

Cortisol

A

Hormones released from adrenal cortex in the stress response

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15
Q

Type 1 IgE Mediated Hypersensitivity

A

Immediate
Local or systemic
Allergen activates IgE when binds to mast cells
At next exposure, the antigen binds with the surface IgE, releasing mediators and triggering the complement system

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16
Q

Type II Cell Mediated

A
Antigens deposit themselves on tissue
Antibody binds to tissue
Complement reaction causing inflammation
Phagocytosis
Cell death
17
Q

Type III Immune Complex Mediated

A

IgM binds to antigen and agglutinates

Accumulates and deposits in the tissue, specifically the blood vessel walls

18
Q

Serum sickness

A

Type III immune complex are formed in the blood and target tissues

19
Q

Arthus reaction

A

Type III immune complex are formed in the walls of blood vessels

20
Q

Type IV Cell Mediated

A

T cells activated from a chemical bound to the proteins in the skin