Adaptive Immunity

Question 1

IgG

Answer 1

Responsible for resistance against many viruses, bacteria and bacterial toxins

Anti-Rh antibodies by Rh-negative mothers
Produce haemolvtic disease of newborn

Question 2

Which antibody class is the largest and most diverse?

Answer 2

IgG

Question 3

Which antibody makes up 80% of all antibodies?

Answer 3

IgG

Question 4

IgE

Answer 4

Attaches as an individual molecule to exposed surfaces of basophils and mast cells
•
•When an antigen is bound by igE molecules
- Cell is stimulated to release histamine and other chemicals that accelerate inflammation
Important in allergic response

Question 5

IgD

Answer 5

An individual molecule on surfaces of B cells, where it can bind antigens in extracellular cells
Binding can play a role in the sensitisation of the B cell involved

Question 6

IgM

Question 7

IgA

Question 8

Cytotoxic T Cells

Answer 8

Release lymphotoxin to kill cells

Question 9

Helper T cells

Answer 9

Regulate the function of B cells, T cells, phagocytes, and other leukocytes

Question 10

Suppressor (regulatory) T cells

Answer 10

Suppress lymphocyte function, thus regulating immunity and promoting self-tolerance.

Question 11

Adaptive immunity

Answer 11

Part of the third line of defence consisting of lymphocytes
Specific immunity that targets specific antigens
Involves B and T cells

Question 12

B cells

Answer 12

Antibody mediated immunity. Produce antibodies that attack pathogens

Question 13

T cells

Answer 13

Cell-mediated immunity; Attack pathogens more directly

Question 14

Stages of Adaptive Immunity

Answer 14

Recognition of antigen
Activation of lymphocytes
Effector phase (immune attack)
Decline of antigen causes lymphocyte death (homeostatic balance)
Memory cells remain for later response if needed