Adaptiv Föreläsning Flashcards by Natthawadee Jaroensuk

Q

Hur tar sig naiva lymfocyter in i SLOs?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Lymfocyternas går till sina särskilda platser med
kemotaktisk migration

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Sekundära lymfoida organens organisation/ mjälte

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Lymfocyternas förmåga att detektera mikrob-varianter beror på
antigenspecifika receptorernas variationsrikedom

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

T cellen detekterar ”sitt specifika antigen” med TCR
presenterat på MHC på en DC i SLO

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CTLA4

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PD1

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Olika Th

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Th1

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Th1

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Th1 cellens effektorfunktioner

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Th2 cellens effektorfunktion

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Th17 cellens effektorfunktion

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CD8+ Tc cellens aktivering

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

DC MHCI precentering

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Lethal hit

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CTL har sekretoriska vesikler

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Antikroppen grek

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Ig-molekylen kan uttryckas både i
membranbunden (mIg) och sekretorisk form (sIg)

A

Q

Antikroppar
B cellens olika differentieringsstadier

A

Q

Antikropparnas funktion och distribution

A

Q

Antikropparnas funktion

A

Q

Neutralisering

A

Q

Opsonisering

A

Klassiska aktiveringsvägen av komplementsystemet

ADCC (Antibody dependent cellular cytotoxicity)

Aktiverar mastceller

T-cellsoberoende B-cellsaktivering

Samarbetet mellan T och B celler: cellerna möts

Antikroppsmedierade immunförsvaret

Den aktiverade B cellen

Vid systemisk infektion

Isotype switch

Upprepad immunisering illustrerar antikroppssvarets Affinitetsmognad

Hur skapar vi tolerans mot oss själva?

Perifer T cells tolerans olika sätt

Perifer T cells tolerans

AIRE

Perifer T cells tolerans

Naturliga CD4 regulatoriska T-celler (tTreg)

Negativ selektion & Agonistselektion - Tregs AIRE The autoimmune regulator protein

Inducerbara Tregs (iTregs)

Treg Generella mekanismer

Sammanfattning Tregs Funktion

Sammanfattning perifer T cells tolerans

B-cells tolerans

Viktiga punkter