Ad Renal Flashcards

1
Q

How to check persistant proteinuria

A

Initial 1+ proteinuria—-> confirm by early morning urine dipstick—-> to check persistant proteinuria - consecutive positive urine dipsticks 1-2 weeks.

Gold standard - 24 hour urinary protein.

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2
Q

Management of Renal artery stenosis

A
  1. Control hypertension- by ACE-I or ARB ( careful monitoring done to renal impairment, if renal signs are seen—> stop them and start CCB.
    Avoid thiazide diuretics.
  2. Control cholesterol- statins
  3. Revascularization by renal artery angioplasty -
    -for patient who failed medical management
    -resistant hypertension
    -dialysis dependent kidney failure
    -BL renal artery stenosis
    -SINGLE kidney with RAS.
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3
Q

PSA elevating and reducing factors

A
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4
Q

Sclerotic changes of vertebrae means

A

Highly suggestive of Prostate cancer with SCLEROTIC changes.

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5
Q

If abnormal DRE or high PSA according to the age , what’s next

A

Transrectal ultrasound scan( TRUS) ( as a guide for biopsy) and prostate biopsy taken.

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6
Q

When to do bone scan in prostate cancer

A

Positive bone scan probability is very low unless PSA >10. So unless it’s >10 ,unnecessary.

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7
Q

What’s goodpasture syndrome / anti glomerular basement membrane disease ( anti- GBM disease)

A

Common in younger <30y
Affects only LUNGS and KIDNEYS.

CF- sob , cough, hemoptysis ( due to alveolar hemorrhage) reduced UOP, dark colored urin.

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8
Q

Diagnostic test for goodpasture syndrome

A

Real biopsy—-> check for anti- GBM antibody

Second most accurate test - anti-GBM antibody assay.

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9
Q

Commonest complication of TURP

A

Retrograde ejaculation (80-90%)

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10
Q

How does TURP syndrome occur

A

By fluid overload ,electrolyte imbalance and hyponatremia.( absorption of fluid which was used to irrigate prostate during the procedure )

CF
CNS- restless, headache, confusion,N/V, cerebral edema
CVS- bradycardia,tachypnea, hypoxia, cyanosis
Hypothermia
Abdominal pain and distention.

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11
Q

What’s gold standard for urine incontinence

A

Urodynamic studies.

Important not for diagnosis but when planning invasive procedures.

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12
Q

Which chronic derangements in CKD are usually well tolerated by the patient

A

Hypercalcemia ( due to impaired bone metabolism)
Hyperkalemia ( failure to excrete potassium)

Hyponatremia( inability to retain sodium by kidneys) and uremia are not well tolerated

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13
Q

What’s neuropathic bladder ?

A

Due to secondary neurological damage.
Symptoms- overflow incontinence ,frequency, urgency, urine retention.
It’s a cause rather than a type of UI.

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14
Q

First line for urge incontinence

A

Bladder training ( first line)
But commonly combined with pelvic floor exercise

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15
Q

In urge incontinence what’s the mx if pelvic floor exercises failed

A

Surgical ( high cure rates) options considered.
1. Mid urethral string (tension free vaginal tape under urethra)
2. Bladder neck sling ( suspension)
3. Urethral bulking agents injection.
4. Burch colposuspension

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16
Q

Ix of choice for urolothiasis

A

CT KUB
X-RAY KUB can be used to minimize radiation

USS - can’t visualize stones but hydeonephrosis can.
MRI HAS NO PLACE HERE.

17
Q

Mechanism of urge incontinence

A

Overactive bladder due to Detrusor instability

18
Q

RF for testicular cancer

19
Q

What are tumor markers of testicular cancer

A

AFP
Beta HCG

20
Q

In suspected testicular tortion what to do

A

Surgery immediately
Window of necrosis 4-6 hours

21
Q

Testicular mass management

A

Initial- USS —-> of cancer suspected or cystic TUMOR MARKERS —-> if positive CT for staging and Mets —-> surgey if indicated

22
Q

What’s the most imp investigation to asses male infertility

A

FSH
>2.5 times normal FSH indicate IRREVERSIBLE TESTICULAR FAILURE.

23
Q

Commonest cause of Hematuria in symptomatic and asymptomatic

24
Q

Which size of rental stones will pass spontaneously

A

Less than 7mm

25
What’s the symptom triad of renal cell carcinoma?
Gross hematuria Flank pain Abdominal mass
26
What’s a small renal mass
Renal lesion of <4cm in the largest diameter is a small renal mass
27
Which features of renal masses make them more likely to be malignant ?
28
Which renal masses are eligible for partial nephrectomy / nephron sparing surgery ?
Smaller then 7cm
29
What’s the management for small renal masses?
If life expectancy MORE THAN 5 YEARS and aGOOD CANDIDATE FOR SURGERY- surgical resection is the best management.
30
Total nephrectomy is the choice of tx with what factors ?
31
Who are good candidates for active surveillance of small renal masses?
Some with CT or MRI scans with 6-12 moth intervals. 1. Small renal masses who are not good candidates for surgery 2. Life expectancy less than 5 years 3. Renal impairment
32
Ablation of small renal masses is the option in what scenarios ?
33
How to manage infertility with absent vas deferens?
In vitro fertilization. Aspirated sperm from testes are injected to oocyte.
34
What’s the urinary condition caused by cyclophosphamide?
Causes hemorrhagic cystitis. Hematuria is painful rather than painless.
35
What are four risk factor for testicular cancer ?
36
What’s the diagnostic test for scrotal cancers?
USS
37
How to manage a cystic testicular mass ?
If a cystic lesion detected in USS, next is to tumor markers ( because 23% testicular cysts are malignant.
38
I hate the next investigation for asymptomatic Hematuria ?
Urine culture