ACVS Board Exam Feb 2007 Flashcards
Calculate heart rate on an ECG
should give paper speed ie 50 mm/sec
Which fluid types have Calcium?
LRS and Plasmalyte 56
Which fluid types do not have Calcium?
Plasmalyte 148 and NormR
Calculate blood donor volume needed for cats
BW(50)(change in PCV desired/donor PCV
Tobias says 50 for cats, other texts say 66-70
Calculate blood donor volume needed for dogs
BW(90)(change in PCV desired/donor PCV)
Which colloid has an oncotic pressure of 30?
Hetastarch 200 (Elohast), COP 25 Hetastarch 450 (Hespan), COP 29-32
Duration of Hetastarch’s colloid effect?
12-24hr (Fossum)
Rough estimate of plasma omolarity?
2 X Na+
Globulins responsible for what % of COP?
20%
MOA Heparin
Potentiates antithrommbin (incr affinity by 10 000X) Low-molecular weight heparin inhibits fXa more than antithrombin
Can reharvest ACBG from prox humerus?
q 8 weeks
Clinical relevance of Swaim paper: wound healing - cats pull peripheral, dogs central VetSurg 2004 Nov-Dec;33(6):579-87
Surgeons should view the cat as a unique species, which presents its own special challenges in wound healing, and should take this into account when planning treatment of feline wounds, either by primary closure, or by second intention healing
Conclusion of Swaim paper: wound healing - cats pull peripheral, dogs central VetSurg 2004 Nov-Dec;33(6):579-87
Significant, previously unreported differences in cutaneous wound healing exist between cats & dogs. In general, cutaneous wounds in cats are slower to heal. Cats & dogs also appear to use different mechanisms o fsecond intention healing. In cats wounds close mainly by contraction of the wound edges, whereas dog wounds close more from central pull, and epithelialization
Definition Totipotent
unlimited, can form whole organism
Definition of Multipotent
(adult) can differentiate into multiple, but limited lineages
Definition of Pluripotent
(embryonic or iPS from adult stem cells) can differentiate into any of the 3 germ layers (endoderm, mesoderm, ectoderm)
TP of less than 2 g/dL will…
slow healing
Chlorhexidine: toxic to tissues at what concentration?
- At 0.05%, lethal to canine embryo fibroblasts (0.5% for povidone-iodine)
- May be ototoxic and neurotoxic
- Use in wounds < or =0.05%
- Use on skin 2-4%
Half life of albumin in a dog?
8 days
Minimum time that g-tube and e-tube must be left in?
7-10 days
Refeeding syndrome
hypophosphatemia
TPN – need central line due to?
osmolarity
Prophy ATBs ideal start time?
> 30 minutes & <60 min prior to incision
Readminister q 3 hours (ie. Two half lives of Cefazolin)
• Tobias=every 2 hours
Best atb’s for anaerobic infection
• Metronidazole, chloramphenicol, clavamox, clindamycin, ampicillin, tetracyclines, macrolides (aminoglycosides ineffective against anaerobes)
Open fracture grade 1-4 - definition
- I=wound smaller than 1 cm
- II=wound >1cm without extensive soft tissue damage
- IIIA=soft tissue damage but adequate coverage
- IIIB=extensive tissue loss, periosteal stripping, bone exposure, contamination
- IIIC=arterial injury requiring repair
Where anatomically do you transplant new kidney along aorta (cats)?
- Renal artery to caudal aorta, proximal to caudal mesenteric artery, end-to-side
- Vein to caudal vena cava, end to side
- If anastomose to iliac vessels, 12% pelvic limb complications
ETO effectiveness at what temp, conc, humidity, time of expo?
- Cycle time inversely related to concentration, temperature, humidity (Fossum)
- Time 2-5 hours
- Concentration 450-1200 mg/L
- Temperature 29-65C (84-149F)
- Humidity 45-85%
Why can you not ETO sterilize once radiated?
Releases toxic compounds
Conclusion of Mison Vet Surg – laser vs. Scalpel
Vet Surg. 2003 Mar-Apr;32(2):153-60.
The CO(2) laser provided better intraoperative hemostasis than CST. However, overall healing and increase in tensile strength of the skin-flap junction of the flaps created by the laser may be delayed during the first few weeks of wound healing.
Clinical relevance of Mison Vet Surg – laser vs. Scalpel
Vet Surg. 2003 Mar-Apr;32(2):153-60.
Skin flaps used to repair large skin defects in dogs can be created and elevated with a CO(2) laser. In areas of increased skin mobility or tension, skin flaps created with CO(2) laser may be more susceptible to complications such as dehiscence, and care should be taken to minimize these complications.
Surgical lasers – Argon vs. CO2 (effects, water absorption)
- Argon LASER (514 nm), energy absorbed by hemoglobin and melanin to heat
- Argon COAGULATION monopolar no touch, coagulation more uniform and shallower than electrosx, uses argon GAS (no water???)
- CO2 LASER(10600 nm), heats intracellular water to boiling, not absorbed by pigmented areas, not absorbed by blood-soaked areas, can’t use with scope, <0.6mm, less edema because CO2 seals lymphatics
Osteopromotion definition
- Results in enhancement of regenerating bone
- Tobias doesn’t state how it differs from osteoinduction
- Example : platelet-rich plasma
Ehrlos Danlos syndrome aka cutaneous asthenia – definition
• Inherited deficiency of type I or III collagen, Himalyan cats
Effect of steroids on wound healing
- Decreased protein synthesis, inhibits lysosomal enzymes, anti-inflammatory
- High doses limit capillary budding, inhibit fibroblasts epithelialization
Halsted’s principles
- Gentle tissue handling
- Hemostasis
- Preserving blood supply
- Aseptic technique
- Elimination of dead space
- Apposition of tissues
Local anesthetic + epinephrine – effect
- Epinephrine 0.1ml to 20 ml anesthetic
- Delays rate of vascular absorption of local anesthetic
- Increases intensity and prolonged anesthetic activity
Best way to administer Gentamicin IV (interval)
- 1-2 mg/lb q8h or 3 mg/lb q24h
- Q24 hrs (Boothe)
- Gentamycin better for staph, amikacin better for Pseudomonas
- Gentamycin more renal toxic than amikacin
Best dosing interval Fluoroquinolones
• Total daily dose once daily (Boothe)
Advantages and drawbacks of everting, inverting suture pattern
- Everting=increased strength across the wound, but may cause local ischemia
- Inverting=use largely replaced by appositional
Effect of hyperbaric chamber O2 on wound healing
- Improved outcome with deferoxamine
* May be detrimental to graft survival
Which mammary gland included in cr. superf. epigastric a.p. flap?
- Cr=glands 3 and 4
* Caudal=glands 2 to 5
Causes of skin graft failure
- Separation of graft from tissue bed (seroma, hematoma, exudation)
- Infection
- movement
4 processes of skin graft take
Adherence,Imbibition, Inosc, Vasc Ingrowth
Advantages of meshing a graft
- Allows drainage
- Covers larger defect
- Reconstruct irregular surfaces