acutely unwelll Flashcards
how do you define shock?
inadequate perfusion; inadequate blood pressure (no oxygen)
cardiac output does not match demand
life threatening generalised form of acute circulatory failure with inadequate oxygen delivery to (and consequently oxygen utilisation) by cells
state of cellular and tissue hypoxia due to either reduced oxygen delivery, increased oxygen consumption, inadequate oxygen utilization, or a combination of these processes
what leads to distributive shock?
inflammation leads to increased vascular permeability
leads to colloid osmotic pressure decreasing
decreased reabsorption at venous end
fluid loss into interstitial space
what leads to hypovolaemic shock?
loss in fluid volume via damaged dermal barrier
what leads to cardiogenic shock?
cardiac stress
what is circulatory shock?
inadequate blood flow results in damage to body tissues
what is hypovolaemic shock?
loss of plasma or blood volume
what is obstructive shock?
obstruction of system
what is distributive shock?
vasodilatory shock; no resistance
what is cardiogenic shock?
heart issues causing circulatory shock
burns leading to distributive shock (fluid in body retained, just not where it should be)
inflammation leads to increased vascular permeability
- damaged tissue releases permeability factors, allows WBCs in, neutrophils release more permeability factors (cytokines etc.)
- formation of fibrin clot
- if burns 15-20% SA - systemic issue (mediators e.g. TNF
hydrostatic pressure»_space; (fluid loss to interstitium)
oncotic pressure «_space;(no ability to draw fluid back from interstitium)
BP falls
leads to colloid osmotic pressure decreasing
decreased reabsorption at venous end
fluid loss into interstitial space
burns causing hypovolaemic shock
fluid evaporation
burns causing cardiogenic shock
venous return «
lower end diastolic volume (less cardiac contractility)
less cardiac output
- if burns 15-20% SA - systemic issue. Mediators leak into bloodstream etc. (mediators e.g. TNF alpha worsen cardiac contractility)
fluid resuscitation: history
volume loss: bleeding, dehydration, vomiting and diarrhoea
volume shift: sepsis, anaphylaxis, neurogenic
previous limited intake, thirst, abnormal loss, comorbidities
fluid resuscitation: examination
signs of fluid loss, cool peripheries, prolonged cap refill, positive 45 degree leg raise
cap refill, pulse, BP, oedema, postural hypotn
cool peripheries, cyanosis, weak peripheral pulses
dry mucous membranes, reduced skin turgor
fluid resuscitation: observations
sys BP < 100mmHg
HR>90
RR>20
NEWS>5