Acute Surgery Flashcards

1
Q

Appendicitis

A

Inflammation of veriform appendix, usually due to obstruction due to faecolith (hardened mass of faeces), foreign body or lymphoid hyperplasia

Sx: RIF pain (peri-umbilical at first then moves to RIF), anorexia, N+V
Signs: Pain at McBurney’s point (1/3 from ASIS to umbilicus), Rovsing’s sign (press on LIF fossa elicits pain on RIF), Psoas sign (pt lies flat, extends leg and pain elicited due to stretching iliopsoas muscle), fever

DDx: Acute cholecystitis, Merkel’s diverticulitis, Testicular torsion, ectoptic, ovarian pathology

Ix: FBC (mild leukocytosis), CT abdo pelvis, USS abdo (exclude ovarian pathology)

Tx: laparoscopic appendicectomy + prophylactic abx
Immediate appendiecectomy not indicated when:
- Advanced peritonitis - IV fluids, IV abx
- Appendix mass
- Resolved

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2
Q

Biliary Colic

A

Gallbladder contracts but outflow obstructed due to stone in neck of gallbladder (Hartman’s pouch) or cystic duct

Sx: Recurrent pain (esp. after eating fatty meal) radiates to r. scapula + epigastric pain
Not systemically unwell unlike acute cholecystitis

Tx: Elective laprascopy cholecystectomy

DDx (abdo colic): 
Ureteric colic (due to stone, tumour)
Bladder colic 
Mechanical obstruction (partial or complete obstruction)
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3
Q

Acute Cholecystitis

A

Inflammation of gallbladder wall due to irritation of conc. bile contained within due to obstruction from gallstone

Sx: RUQ pain + fever
Signs: Fever, Positive Murphy’s sign (palpation of RUQ n+inspiration causes pain (as gallbladder moves down) and no pain on LUQ, palpable gallbladder

Ix: FBC (leukocytosis), LFTs (cholestatic: elevated Alk phos, bilirubin), Abdo USS (gallstones, thickened wall, pericholecystic fluid)

Tx: IV fluids, IV abx, NBM + Cholecystectomy

DDx: Acute pancreatitis, Perf DU

Complications:
Empyema, gangrene, perforation

Indications for cholecystectomy:

  • Single complication
  • Asymptomatic pts if at risk of complications e.g. diabetics
  • Diabetics, history of pancreatitis

Complications of cholecystectomy:
Leakage of bile, jaundice

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4
Q

Obstructive jaundice

A

Stone in CBD

Sx: Pale stools, dark urine
Signs: Jaundice

DDx:
with jaundice: pancreatic carcinoma, cholangiocarcinoma, acute hepattis
without jaundice: intestinal obstruction

Ix: LFTs (Raised Alk phos), Abdo USS (gallstones, dilation of CBD >7mm), MRCP, ERCP
Tx: ERCP

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5
Q

Dx of stones in CBD:

A
With jaundice: 
- Pancreatic Ca. 
- Cholangiocarcinoma
- Hepatitis 
Without jaundice: 
- Intestinal obstruction 
- Renal colic
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6
Q

Ascending Cholangitis

A

Stone obstructing CBD + infection proximal to blockage

Sx: RUQ + fever + jaundice
Reynauld pentad: RUQ pain + fever + jaundice + low BP + confusion

Tx: ABCDE, IVF, catheter, IV abx, HDU/ITU (if septic shock)
Urgent ERCP

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7
Q

Complications of ERCP

A

Pancreatitis, haemorrhage, perforation

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8
Q

Acute pancreatitis

A

Inflammation of pancreas due to autodigestion of pancreatic enzymes

Sx: Epigastric pain radiates to back, N+V
Signs: Tachy, fever, shock, Cullens sign (periumbilical bruising), Grey Turner’s sign (flank bruising)

Ix: FBC (anaemia, leukocytosis), Amylase (3x higher ULN), LFTs (raised bilirubin), ABG (hypoxia), USS (gallstones), CT abdo (necrosis, abscess, pseudocyst)

Tx: Supportive (analgesia, IV fluids, NBM (give pancreas rest), NG tube)

Glasgow Imrie score: 3 or more in 48hr = severe
PaO2
Age >55
Neutrophils
Calcium (low)
Renal (urea)
Elevated enzymes: AST, LDH
Albumin
Sugar (BM)

Complications:
abscess, necrosis, diabetes, renal failure (due to shock)

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9
Q

Gallstone ileus, Mirizzi syndrome

A

Stone causing SBO (usually in terminal ileum). Usually enters via cholecystoduodenal (between gallbladder and duodenum) fistula

Rigler’s triad: Pneumobilia (air in biliary tree), SBO, gallstones

Ix: Abdo XR: pneumobilia, dilated small bowel loops, gallstones

Tx: IV fluids, abx, NBM, NG tube
Enterotomy (excision of intestines) + stone removal

Mirizzi syndrome
Gallstone in neck of gallbladder leading to compression/obstruction of common bile duct or common hepatic duct
Tx: Lap choly

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10
Q

Causes of pancreatitis

A
Gallstones
Ethanol
Trauma 
Steroids
Mumps
Autoimmune
Scorpion bite
Hypercalcaemia
ERCP
Drugs (Azathioprine, NSAIDs, thiadize)
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11
Q

Peritonitis

A

Infection of peritoneum

Aetiology: E.coli, Strep faecalis, pseudomonas

Causes: Trauma, perforation (peptic ulcer, appendix), acute cholecystitis, septicaemia

Sx: Severe pain radiates to shoulder, vomiting
Signs: fever, rigid abdo, rebound tenderness, no bowel sounds
If advanced: Abdomen distended+tympanic (high pitched due to air), Hippocratic facies (sunken eyes, skin is cold)

Ix: FBC (leukocytosis), Amylase (exclude pancreatitis), 
Erect CXR (air under diaphragm or perforated abdominal viscus (if perforated peptic ulcer), CT abdo (free gas, locate cause)

DDx: MI, AAA, intestinal obstruction

Tx: O2 (if <95%), IV fluids, abx, NG tube, analgesia, surgery (if infection can be removed e.g. peptic ulcer repair/appendiectomy)

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12
Q

Diverticulitis

A

Diverticula of colon are outpouchings of mucosa through muscle wall (usually sigmoid)

True diverticulum: outpouching covered by all layers of bowel (Merkel’s diverticulum)
False (outpouching lacking normal muscle layer (colonic diverticula)

Causes: low fibre diet, obesity, smoking

Complications of diverticula:

  • Diverticulitis (inflammation of diverticula) leading to perforation - peritonitis, fistula with small bowel/bladder
  • Large bowel obstruction
  • Haemorrhage

Sx: LIF pain, altered bowel habits, PR bleeding
Signs: fever, guarding, vague mass on LIF, PR bleeding

Sx chronic divertilcular disease:
Changes in bowel habit, LBO, PR bleed (mucus, bright red)

Ix:
FBC (leukocytosis)
CXR (free air under diaphragm if perforation)
CT (thickened bowel wall, mass, abscess, fistula (between colon and bladder)
flexible sigmoidoscopy (exclude colon Ca)
CT colonography

DDx: IBD, colon ca.

Tx:
Supportive, high fibre diet, laxative

Diverticulitis:
Sx: fever, raised WC, signs peritonitis

Tx:
Acute: Supportive - NBM, IV abx, analgesia
Surgery: if fails respond to medical management, complications - perforation, abscess, obstruction

Abscess: Sx: swinging fever, increased WCC, Ix: US, abx+percutaneous drainage

Peritonitis due to perforation: Laparotomy (Hartman’s: sigmoidectomy + end colostomy) + abx

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13
Q

Visceral perforation

A

Perforation along GI tract

Causes: Peptic ulcers, sigmoid diverticulum, toxic megacolon, mesenteric ischaemia (due to infarction of intestinal tissue), recent surgery

Sx: pain, acute onset, vomting
Signs: peritonitis (rigid abdomen), septic

DDx: Acute pancreatitis, MI, ruptured AAA

Ix: 
FBC (raised WBC)
Urinalysis (exclude renal and ovarian pathology)
Erect CXR: free air under diaphragm
CT: (location of perforation) 

Tx: IV abx, IV fluid, NBM, analgesia
Surgical: Repair peptic ulcer with omental patch, repair diverticulum (Hartmann’s)
Wash-out

Complications: Sepsis, haemorrhage

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14
Q

Upper and Lower GI bleeding

A

Management: Assessment+resus, diagnosis of source of bleeding, treat bleeding

Assessment:
Sx: haematemesis, malaena
Signs: pupura (bleeding disorder), features liver disease (oesophageal varices), history of peptic ulcers (NSAIDS, H Pylori)

O2, IV fluids, Group and Save

Causes:
Oesophagus: Varices, Mallory Weiz tear, Borhaave’s syndrome
Stomach: Gastric ulcer, tumours,
Duodenum: Duodenal ulcer,
Small bowel: Meckel’s diverticulum, tumours
Large bowel: Diverticulitis, colitis (UC, ischaemic colitis), tumours

Ix: FBC
UEs (Urea high + low HB = upper GI bleed)
Coag screen
LFTs (liver disease)
Upper GI endposcopy (locate site of bleed, peptic ulcers can be treated with adrenaline)
Colonscopy: locate colonic sources

Tx:
Blood transfusion
Indications surgery: Bleeding despite endoscopic treatment

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15
Q

Ruptured AAA

A

Aneurysm: abnormal permanent dilation of aortic a

Sx: Severe back pain, radiation to groin
Signs: pulsatile mass

Ruptured:
Sx: Severe back pain, syncope, vomiting
Signs: Haemodynamically compromised: hypo, tachy
Triad of rupture AAA: Back pain, hypotensive, pulsatile mass

Ix: USS, CT with contrast

DDx: renal colic, MI

Tx: 
<5.5cm
- Smoking cessation
- BP control
- Statin, aspirin

Indications for surgery:
>5.5cm
expanding >1cm/yr
symptomatic

  • Endovascular aneurysm reapir (EVAR) - stent via femoral artery at aneurysm (decrease hospital stay after but higher rate of reintervention so not for younger pts)
  • Open surgical repair (OSR) - (midline laparotomy - aneurysm replaced with graft)

Rupture:
Tx: O2, IV access (2 large bore cannulae), bloods (FBC, UEs, coag), crossmatch
Tx: prophylactic co-amox, straight to theatre
If unstable: open repair
If stable: CT to see if suitable for endovascular repair

Complications of AAA: rupture, retroperitoneal leak, embolisation, MI (coronary a. disease already common, surgery causes extra stress due to cross clamping aorta), aortoduodenal fisutla

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16
Q

Acute limb ischaemia

A

Sudden decrease in limb perfusion due to partial/complete arterial occlusion which threatens viability of limb

Causes: Embolus, thrombus in situ, trauma

Sx: Pain, pallor, parathesia, pulseless, perishingly cold, paralysis

DDx: chronic limb ischaemia, acute DVT, SC compression

Ix: FBC (anaemic), Group and Save,
ECG (AF), lactate (assess level of ischaemia), doppler US (biphasic in normal and monophasic in hardened arteries), CT arteriogram (site and extent of blockage)

Tx: O2, Heparin bolus and infusion
Surgical
1st line: Baloon catheter embelectomy (Fogarthy catheter)
2nd line: open thromboembelectomy 
non-viable: amputation
17
Q

Acute urinary retention

A

Acute retention: inability to pass urine, suprapubic pain, suprapubic mass
Chronic: Gradual enlargement of bladder, dribbling, incontinence, little/no pain

Management:
Diagnose cause
Assess renal damage
Asses general condition of pt

Signs: Suprapubic tenderness, enlarged bladder dull to percussion

Diagnose cause: 
Urinary stone, tumour , faecal impaction
Acute causes: 
BPH 
Prostatic Ca
Urethral stricture
Drugs: Anitmuscarinics (decreased bladder sensation), Sympathomimetics (increases muscle tone for urethral sphincter), opioids (decreased bladder sensation) 
Neurological impairment (more chronic cause) - SC injury

Ix:
FBC (haematuria, infection)
PSA (do NOT check for Acute urinary retention) - raised in prostate ca, retention, infection, catheter)
UEs (renal impairment)
Urinalysis (infection)
PR (prostate enlargement, mass, anal tone)
US bladder (diagnostic) - post void residual vol >300ml: chronic

Tx:
Catheter
Treat underlying cause (BPH - Tamsolosin (a1 receptor antagonist - relaxation of smooth muscle bladder and prostate
Finasteride (5-alpha reductase inhibitor - stops conversion of testosterone into DHT, makes prostate smaller)

Complications:
Infection, AKI

18
Q

Haematuria

A

<3 RBCs/HPF (high power field) either visible (gross/frank) or non-visible (microscopic or dipstick)

Risk fx: Male, smoking, chemical exposure (aromatic amines), recurrent UTIs

Causes:
Glomerular: IgA nephropathy, Alport’s syndrome (hereditary nephritis)
Non-glomerular:
Upper tract - Pyelonephritis, renal stone, renal cell cancer
Lower tract - UTI, BPH, transitional cell carcinoma
Psuedo-haematuria: menstruation, beets, drugs (rifampicin)

Ix: 
UEs (renal function)
Urinalysis (UTI)
Urine culture 
PSA (prostate ca)
Cystoscopy 
US KUB (Upper urinary tract) (renal stones)
19
Q

Testicular pain

A

Surgical emergency - torsion of spermatic cord leading to strangulation of gonadal blood supply which can cause testicular necrosis

Sx: Sudden onset pain in groin/lower abdo + vomiting
Signs: swollen scrotum, cremasteric reflex absent (testicle pulled up when inner thigh stroked)

Risk fx: trauma, straining, lifting

DDx: Strangulated inguinal hernia, epididymitis (UTI, STI, urethral stricture), appendicitis

Ix: Scrotal US (see if there is testicular perfusion)

Tx: Surgical exploration and detorsion - untwist spermatic cord and sutured to tunica vaginalis. Fixation of other testis

20
Q

Head trauma

A

A-E
Assess cervical spine: hard collar
Ay: GCS <8 requires anaesethetics
B: ABG
C: Raised ICP (brady, hypertension), hypotension rarely due to head trauma but other cause e.g. ruptured spleen
D: GCS, pupils, BM
E: fractures, laceration, basal skull fractures (racoon eyes, bruising behind ear, blood from ear)

Red flags: dilated pupils (cerebral compression), signs basal skull fracture, focal neuro deficit

Ix: CT head, CT C spine

Neuro referral:
GCS <8
Unexplained confusion >4hrs
Focal neuro signs

21
Q

Sepsis (cellulitis, abscess)

A

Cellulitis (inflammation of connective tissue)
Cause: B-haemolytic Group A Streptococcus

Signs: skin is red, hot, blanches on pressure, cutaneous gangrene

Tx: Immbolisation, Abx, Observe (nec fasc)

Abscess: localised collection of pus
Cause: Staph. aureus

Sx: swinging fever, malaise
Signs: hard, red, painful
Tx: drainage

22
Q

Blood transfusion: acute transfusion reactions

A

Complications:
Acute transfusion reactions
Pulmonary complications
Transfusion transmitted infections

Sx of acute transfusion reactions: Fever, Tachy, hyper/hypotension, flushing
Tx: Stop transfusion, A-E

Mild transfusion reactions
Causes: febrile non-haemolytic transfusion reactions, mild allergic reaction
Tx: paracetamol, restart at slower infusion

Moderate transfusion reactions
Tx: IV chlorampenamine (anti-histamine), steroids, salbutamol nebs, IM adrenaline (treat like prophylaxis)

Severe transfusion reactions:
- Acute haemolytic transfusion reaction - ABO incompatibility
Sx: feeling of apprehension, flushed, SOB
Signs: dark urine (haemolysis), fever, hypotension
- Bacterial contamination
Sx: cloudy urine (platelets in urine)

23
Q

Pulmonary complications of blood transfusion

A

TACO (transfusion associated circulatory overload)
- Circulatory overload
Acute onset of respiratory distress within 24 hrs of transfusion

Risk fx: Age, pre-existing HF or renal impairment

TACO checklist required before blood transfusion
How to prevent TACO:
Take pts weight into account, fluid balace, slower transfusion

TRALI (transfusion associated acute lung injury)
- Immune mediated
Acute dyspnoea with hypoxia and bilateral pulm infiltrates in 6hrs of transfusion
- HLA/HNA antibodies from donor

24
Q

Blood transfusion: Transfusion transmitted infections

A
Causes: 
Bacterial contamination 
- Can occur with platelets 
Viral 
Parasitic
Prion 

Occurs in less than 8 in 100,000 people

25
Q

Delayed haemolytic transfusion reaction

A

Pts antibody attach to donor’s RBC which causes haemolysis

Fever + signs of haemolysis more than 24 hrs after transfusion
Signs of haemolysis: decreased HB, increasing bil, LDH, DAT +ve

26
Q

Main adverse events of blood transfusion

A

Errors

9 opportunities for error

27
Q

When to transfuse someone

A

Peri-operative
Massive haemorrhage
Chronic transfusion

IDA doesn’t need transfusion without haemodynamically instability
<80 - likely to be beneficial
80-100 - if pre-existing cardio disease

Indications for special requirements:
Pregnancy
Sickle cell pts
Pts with IgA deficiency

Irradiated blood products: prevents transfusion associated graft vs host disease
For immunosuppressed groups

28
Q

Peptic ulcer

A

Break along lining of GI tract to muscularis mucosae. Usually at lesser curve of stomach or duodenum (gastric or duodenal)

Sx: epigastric pain, nausea, bloating
Complications: perf, bleeding

Causes: H. Pylori or NSAIDs

Ix: H.pylori urea breathe test, H.pylori antibodies, stool antigen test for H.pylori, OGD

Tx: triple therapy: PPI + abx (omeprazole + amox + clary/ met)
surgery:
gastric: antrectomy + Roux en Y gastroenterostomy
duodenal : partial gastrostomy + selective vagostomy

Perforated peptic ulcer:
Sx: severe pain, haemoydyanically unstable
Signs: rigid abdo, silent BS

Ix: Erect CXR (air under diaphragm)
CT (intraperitoneal air) - gold standard

Tx: NG, IV fluids, IV abx
Surgery: omental patch + peritoneal lavage