Acute Respiratory Distress Syndrome Flashcards
Annual incidence of ARDS pre-covid
60 cases/100,000 population
Clinical syndrome of severe dyspnea of rapid onset, hypoxemia, and diffuse pulmonary infiltrates leading to respiratory failure
Acute Respiratory Distress Syndrome
Most common cause of ARDS
Sepsis and Pneumonia (~40-60%)
Trauma patients with APACHE score of ____ have a 2.5-fold increased risk of developing ARDS
> /= 16
In this phase of ARDS, alveolar capillary endothelial cells and type 1 pneumocytes are injured
Exudative Phase
In this phase of ARDS, edema fluid that is rich in protein accumulates in the interstitial and alveolar spaces
Exudative phase
In this phase of ARDS, hyaline membrane whorls are seen.
Exudative Phase
Xray finding of ARDS
Opacities consistent with pulmonary edema, and often involves 3/4 of the lung field
Chest CT scan finding in ARDS
Presence of bilateral pulmonary infiltrates
Phase in ARDS where 1st signs of resolution is evident
Proliferative phase
In ARDS, presence of ____ in lung biopsy, in any phase of the disease, increases risk of mortality
Pulmonary Fibrosis
Function of PEEP
Promotes alveolar recruitment
This intervention provide significant reduction in 28-dag mortality for patients with SEVERE ARDS
Prone positioning
Principle of Fluid Management in ARDS
Maintain low left atrial filling pressure
Fluid restriction and Diuretics limited only by hypotension and hypoperfusion
Only Category A recommendation in management for ARDS
Low tidal volume
