Acute Phase Reactants

Question 1

The most sensitive but not specific acute phase Reactant . Binds receptor phagocytic Cells

Answer 1

C- reactive Protein

Question 2

Peak time for C- reactive Protein

Answer 2

48hrs increases 1000x

Question 3

Acute phase reactant that Activates Monocyte and macrophages producing inflammatory molecules

Answer 3

Serum Amyloid

Question 4

Serum Amyloid produced in the liver transported by ______

Answer 4

HDL

Question 5

Binds in the Fc Portion of an Antibody that functions in Opsonization , Chemotaxis and lysis of Cell

Answer 5

Complement

Question 6

An APR that Limits the harmful effects of immune system by inhibiting proteases release from leukocytes and regulating expression of proinflammatory Cytokines

Answer 6

alpha 1 antitrypsin

Question 7

Deficiency of Alpha 1 antitrypsin will lead to this 2 types of Disease

Answer 7

Pulmonary Emphysema

Juvenile Cirrhosis

Question 8

Antioxidant, Binds irreversibly to free hemoglobin

Answer 8

Haptoglobin

Question 9

Apr that promotes Clot Formation

Answer 9

Fibrinogen

Question 10

Apr that is a principle Copper Transporting Protein in Plasma

Answer 10

Ceruloplasmin

Question 11

Give the 3 Negative Acute Phase Reactants . That will Decrease if theres and inflammation or Infection

Answer 11

Albumin
Pre Albumin/ Transthyretin
Transferrin

Question 12

APR is Driven by _____

Answer 12

IL-6