Acute Inflammation

Question 0

What are the local effects of acute inflammation?

Answer 0

RUBOR
TUMOR
CALOR
DOLOR
Loss of function

Question 1

What are the four processes by which neutrophils migrate?

Answer 1

Margination
Rolling
Adhesion
Emigration

Question 2

What are the systemic effects of acute inflammation?

Answer 2

Forced rest
Loss of appetite
Increased production of CRP

Question 3

Chemical mediators responsible for RUBOR?

Answer 3

Histamine
Leukotriene
Prostaglandin

Question 4

Chemical mediators responsible for TUMOR?

Answer 4

Leukotriene

Prostaglandin

Question 5

Chemical mediator responsible for CALOR?

Answer 5

Prostaglandin

Bradykinin

Question 6

Chemical mediator responsible for DOLOR?

Answer 6

Prostaglandin

Bradykinin

Question 7

What are the causes of acute inflammation?

Answer 7

Microbial infections
Hypersensitivity reactions
Physical agents
Chemicals
Tissue necrosis

Question 8

List the three changes in tissues.

Answer 8

Changes in blood flow
Exudation of fluid into tissues
Infiltration of inflammatory cells

Question 9

Describe the changes in blood flow.

Answer 9

Transient vasoconstriction of arterioles, followed by vasodilator ion of arterioles and capillaries. Increased permeability of vessels to allow exudation of fluid and therefore swelling.

Question 10

List the characteristic microscopic features of acute inflammation.

Answer 10

Oedema
Vasodilatation
Neutrophil margination and migration