Acute Inflammation

Question 1

What are some of causes of acute inflammation with examples?

Answer 1

• physical agents e.g heat cold, radiation
• irritants/corrosive - acids or alkaloids
• microbial infections - pyogenic bacteria
• immune-mediated hypersensitvity e.g. allergic rhinitis
• tissue necrosis (ischaemia from myocardial infarction)

Question 2

What are the 5 classical signs of acute inflammation?

Answer 2

1. redness
2. heat
3. swelling
4. pain
5. loss of function

Question 3

Why do the classic signs appear?

Answer 3

They are trying to prevent further tissue damage and bring cells of the immune system to the site of injury

Question 4

What is the response rate, onset, type of immunity

predominant cell, duration and vascular response of acute inflammation?

Answer 4

Response - Immediate reaction 
Onset - rapid
Immunity - Innate 
Predominant cell - Neutrophil 
Duration -hours to weeks
Vascular response - prominent