Acute Inflammation

Question 1

What are the four signs of acute inflammation?

Answer 1

Calor - heat
dolor - pain
rubor - redness
tumor - swelling

loss of function can also be considered.

Question 2

How does acute inflammation start?

Answer 2

Sensation: Cells in the body sense damage or invasion. The cells include Langerhans/dendritic cells, mast cells, and macrophages.

Question 3

What types of receptors are involved in acute inflammation?

Answer 3

1. TLRs - sense cytokines/extracellular DAMPs or PAMPs
2. NLRs - sense intracellular DAMPs or PAMPs
3. Fc receptors - responsible for Ab mediated effects.