Acute Hepatology

Question 1

Management of Paracetamol Overdose

Answer 1

options of
- activated charcoal
- N-acetylcysteine

*but make sure to MEASURE LEVELS
* WAS IT STAGGERED OR SINGLE DOSE OD?
* consider ACIDOSIS = cause of concern = indication for liver transplant

Question 2

Side effect of N-acetylcysteine

Answer 2

non-IgE mediated MC release = anaphylaxis

therefore

NAC must be infused over an hour to prevent this adverse reaction.