Acute Coronary Syndromes Flashcards
What are the acute coronary syndromes?
- Unstable angina
- NSTEMI
- STEMI
What are the risk factors for ACS?
- Age
- Male sex
- CVD e.g. HTN, atherosclerosis
- Smoking and alcohol
- Sedentary lifestyle and obesity
- FHx
What does the Left Coronary Artery divide into?
- Left circumflex
- Left anterior descending
- Left marginal (anterior branch of the Left Circumflex)
What does the right coronary artery divide into?
- Right marginal
- Right posterior descending
Which leads show the Left Circumflex Artery?
I, aVL, V5, V6
Which leads show the Left Anterior Descending?
V1-V4
Which leads show the Right Marginal?
I, II, aVF
Which areas of the heart are supplied by the Left Circumflex?
- LA
- Posterolateral LV
Which areas of the heart are supplied by the Left Marginal?
Left Ventricle
Which areas of the heart are supplied by the Left Anterior Descending?
- Anterior LV (majority of LV supply)
- Apex
- Interventricular septum
Which areas of the heart are supplied by the Right Marginal?
- Right ventricle
- Interventricular septum
Where does the Posterior Descending artery originate?
- Usually (70%) from the RCA
- Some come from the left circumflex artery
What ultimately drains the arteries’ deoxygenated supply?
Coronary sinus
Describe the pathophysiology of ACS.
Occlusion of the coronary arteries
- Ruptured plaque/thrombus occluded the coronary artery(s)
- Ischaemic damage from hypoxia
How would ACS present?
- Central crushing/visceral pain
- Radiation to jaw or arm
- Sympathetics- N&V, sweating, palpitations
- Dyspnoea
What is a silent MI and who gets them?
Diabetics
- MI without chest pain
What signs might you see on examination?
- Tachycardia
- Dyspnoea
- Tachypnoea
What timeframe of symptoms would you consider for ACS?
- Symptoms at rest for 20+ minutes
- If less than 20 minutes, consider stable angina
What bloods would you do for ACS?
- Troponin- baseline, 3-6 hours, 12 hours
- CK-MB
- Full profile
What imaging is useful in ACS?
- CXR - cardiomegaly may occur, will also show other differentials such as MSK and pneumonia
- ECHO - post-MI function of the heart
- CT coronary angio
What might an ECG show for a STEMI?
- ST elevation
- New LBBB
What might an ECG show in an NSTEMI?
- ST depression
- T wave inversion
- Q waves if late presentation
What score is used for risk of death and recurrence in NSTEMI?
Grace Score- 6 month risk
Outline the Grace Score.
<5% Low risk
5-10% Moderate risk
10+% High risk