Acute Coronary Syndrome Flashcards
What is ACS?
Umbrella term for acute diseases of ischaemic heart disease
What are the 3 diseases in ACS?
- STEMI
- NSTEMI
- Unstable angina
What are the risk factors for ACS? (8 things)
- Age
- Male
- FHx
- Smoking
- DM
- Obesity
- HTN
- Hypercholesterolaemia
What are the clinical features of ACS? (6 things)
- Central crushing chest pain
- Pain radiation to jaws / arms
- SOB
- Feeling of impending doom
- Palpitations
- Nausea + vomiting
(Symptoms @ rest for 20 mins +)
What does the Right Coronary Artery supply? (4 things)
- Right atrium
- Right ventricle
- Inferior aspect of Left Ventricle
- Posterior aspect of septum
What does the Left Coronary Artery give off? (2 things)
- Circumflex Artery
- Left Anterior Descending (LAD)
What does the Circumflex Artery supply? (2 things)
- Left atrium
- Posterior aspect of Left ventricle
What does the Left Anterior Descending Artery supply? (2 things)
- Anterior aspect of Left ventricle
- Anterior aspect of septum
What artery is the Right atrium supplied by?
Right Coronary Artery
What artery is the Right ventricle supplied by?
Right Coronary Artery
What artery is the Left Atrium supplied by?
Circumflex Artery (branch of LCA)
What artery is the Anterior aspect of the Left Ventricle supplied by?
Left Anterior Descending Artery (LAD) (branch of LCA)
What artery is the Posterior aspect of the Left Ventricle supplied by?
Circumflex Artery (branch of LCA)
What artery is the Inferior aspect of the Left Ventricle supplied by?
Right Coronary Artery
What artery is the Anterior aspect of the septum supplied by?
Left Anterior Descending Artery (LAD) (branch of LCA)
What artery is the Posterior aspect of septum area supplied by?
Right Coronary Artery
What investigations should you do in sus ACS? (5 things)
- ECG
- CXR
- Blood
- Cardiac enzymes
- Echo
What are the ECG changes in a STEMI? (3 things)
- ST elevation (in leads of area of ischaemia)
- New LBBB
- Pathological Q wave
What are the ECG changes in a NSTEMI / unstable angina? (2 things)
- ST depression
- T wave inversion (deep)
What does a pathological Q wave suggest?
Deep infarct (late sign)
What is the heart area supplied by the Circumflex Artery?
Lateral
What are the ECG leads for the Circumflex Artery?
- I
- aVL
- V5-6
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What is the heart area supplied by the LAD?
Anterior
What are the ECG leads for the Anterior (LAD) part of the heart?
V1-2
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What is the heart area supplied by the Circumflex artery?
Lateral
What are the ECG leads for the Right Coronary Artery? (3 things)
- II
- III
- aVF
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What is the heart area supplied by the RCA?
Inferior
What are the ECG leads for the Inferior (RCA) part of the heart? (3 things)
- II
- III
- aVF
What should you look for in a CXR of sus ACS? (3 things)
- Cardiomegaly
- Pulm oedema
- Widened mediastinum
What bloods should be done for sus ACS? (5 things)
- FBC
- U&Es
- Glucose
- Lipids
- Cardiac Enzymes (troponin)
What are you checking for in a FBC of sus ACS?
Anaemia
When should U&Es be done in sus ACS?
Before ACEi + other meds
What is seen on an Echo of ACS?
Regional wall abnormalities
Apart from ACS, what are some other causes of raised troponin? (5 things)
- Sepsis
- Aortic dissection
- Myocarditis
- Pulmonary embolism
- Chronic renal failure
What is needed for a diagnosis of ACS? (6 things)
Raised troponin + one of the following:
- Ischaemia symptoms
- ECG: Changes of new ischaemia
- ECG: Pathological Q waves
- Echo: New loss of myocardium
- Echo: Regional wall motion abnormalities
What are the treatment options for a STEMI? (2 things)
- Primary PCI (if available within 2 hrs of presentation)
- Thrombolysis (if PCI not available within 2 hrs)
What is PCI? (4 things)
Percutaneous Coronary Intervention
- Catheter into brachial / femoral artery, up to coronary arteries (XR guided)
- Inject contrast to identify blockage area
- Balloon to widen gap / device to remove or aspirate blockage
- Stent inserted
What is the treatment for a NSTEMI? (6 things)
- B - Beta blockers
- A - Aspirin (300mg)
- T - Ticagrelor (180mg) (antiplatelet)
- M - Morphine
- A - Anticoagulant (Fondaparinux)
- N - Nitrates (GTN)
BATMAN
What score determines if a NSTEMI patient needs a PCI?
GRACE score
What does the GRACE score determine in a NSTEMI patient?
6 month risk of death / repeat MI
What does the patient have to score in the GRACE score to have a PCI?
Medium / high risk (of having repeat MI / death in next 6 months)
How do you prevent a second MI from happening MEDICALLY? (6 A’s)
- Aspirin (75mg once daily)
- Another antiplatelet (clopidogrel / ticagrelor)
- Atorvastatin (80mg once daily)
- ACE Inhibitors (e.g Ramipril 10mg once daily)
- Atenolol
- Aldosterone antagonist
How do you prevent a second MI from happening LIFESTYLE WISE? (5 things)
- X Smoking
- X Alcohol
- Mediterranean diet
- Cardiac rehab (specific exercises)
- Better treatment for other conditions (e.g DM / HTN)
What are the complications of an MI? (5 things)
- D – Death
- R – Rupture of heart septum / papillary muscles
- E – Edema
- A – Arrhythmia / Aneurysm
- D – Dressler’s Syndrome