acute confusional state [delirium] Flashcards

1
Q

define

A

Globally impaired cognition and impaired consciousness

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2
Q

epidemiology

A

20% of elderly patients on medical and surgical wards

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3
Q

aetiology

A
  • DELIRIUMS
  • Drugs: opioids, anticonvulsants, sedatives, L-DOPA, recreational, EtOH/Dx withdrawal, post-general anaesthetic
  • Eyes, ears and other sensory deficits
  • Low O2 states: MI, stroke, PE, respiratory, cardiac failure
  • Infection: pneumonia, UTI, malaria, wounds, IV lines, encephalitis, meningitis
  • Retention: stool or urine
  • Ictal: epilepsy, non-convulsive status epilepticus
  • Under- hydration / -nutrition: dehydration, thiamine, nicotinic acid, B12 deficiency
  • Metabolic: DM (↑↓ glucose), Anaemia, sodium, uraemia, liver failure, malnutrition (beri-beri)

Subdural haemorrhage or other intracranial pathology (SOL, ↑ICP)

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4
Q

clinical features

A
  • Can last weeks to months
  • DELIRIUM
  • Disordered thinking: slow, rambling, incoherent ideas
  • Emotions:Labile mood
  • Language impaired
  • Illusions/delusions/hallucinations: Tactile or visual
  • Reversal of sleep–awake cycle
  • Inattention: attention is poor
  • Unaware/disorientated: person, place and time

Memory deficits: Often marked (amnesic post-episode)

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5
Q

ix

A
  • Bloods: FBC, U+E, LFTs, glucose, ABG, blood cultures, malaria flm
  • Urine dip
  • Septic screen: urine dip,
  • CXR, CT/MRI
  • ECG, LP
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6
Q

rx

A
  • ID and Rx underlying cause
  • Surround w/ familiar people
  • Nurse in moderately lit, quiet room, same staff (minimise confusion)
  • Find glasses, hearing aids…
  • Avoid sedatives if possible, but if disruptive:
  • Haloperidol 0.5-2mg PO/IM OR olanzapine
  • Chlorpromazine 50-100mg PO/IM (avoid in elderly)
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7
Q

ddx

A
  • Anxiety
  • Psychosis
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