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Pharmacotherapeutics - Final > Acute Colitis > Flashcards

Acute Colitis Flashcards

1
Q

4 abx with high risk for c.diff

A

clindamycin
cephalosporins
fluoroquinolones
augmentin

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2
Q

t/f: all abx carry some risk for c.diff

A

t!

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3
Q

2 abx that are moderate risk for c.diff

A

sulfonamides -> bactrim
macrolides

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4
Q

4 low risk abx for c.diff

A

doxycycline
aminoglycosides
metronidazole
vanco

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5
Q

3 sx of acute colitis

A

fever
mucoid stools
onset w.in hours

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6
Q

CT findings of acute colitis

A

ileal and colonic bowel wall thickening w.o obstruction

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7
Q

management of inpt acute colitis

A

fluids: LR 2L
oral rehydration
antiemetics
abx

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8
Q

abx for cdiff

A

po vanco
metronidazole

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9
Q

moa of vanco and metro

A

inhibit cell wall synthesis

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10
Q

3 s.e of vanco

A

redman
ototoxicity
nephrotoxicity

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11
Q

s.e of metro

A

disulfram rxn

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12
Q

what lab needs to be monitored for pt on metro

A

LFTs in elderly

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13
Q

doc for salmonella

A

cipro
alt: bactrim

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14
Q

when are f.u stool cultures recommended in acute colitis management

A

pt’s working in industries handling food or pt care

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15
Q

negative cultures for what 3 organisms are required if stool cultures are needed (food/healthcare workers)

A

salmonella
shigella
shiga toxin producing e.coli

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16
Q

how do you know when you’ve adequately rehydrated pt on IVF

A

adequate urine production

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17
Q

first line antiemetic for hospitalized pt

A

zofran 4 mg IV q4 hr

alt: phenergan

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18
Q

phenergan can be __ toxic (2)

A

liver
vaso

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19
Q

2 adverse effects of reglan (metoclopramide)

A

GI bleed
renal impairment

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20
Q

empiric abx doc for inpt bacterial colitis

A

ceftriaxone
OR
levofloxacin

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21
Q

when should you start abx for bacterial colitis

A

immediately after stool culture (don’t wait for result -> target after if necessary )

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22
Q

t/f: most patients w. AKI should be hospitalized

A

t!

fluid replacement

23
Q

what 3 food borne bacteria are associated w. bloody diarrhea

A

e.coli
shigella
campylobacter
+/- salmonella

24
Q

mc cause of HUS

A

e.coli

25
Q

3 sx of HUS

A

elevated BUN/Cr
hemolytic anemia
thrombocytopenia

26
Q

what bacteria causes travelers diarrhea

A

e.coli (etec)

27
Q

what bacteria do you think of when you see “rice water stools”

A

vibrio

28
Q

what do you think when you see: bloody, water, mucus and pus diarrhea with fever

A

shigella

29
Q

what food borne pathogen is associated w. bacteremia

A

salmonella

30
Q

what food borne bacteria is associated w. GB and reactive arthritis

A

campylobacter

31
Q

what food borne bacteria has a prodrome of fever, HA, myalgia, malaise

A

campylobacter

32
Q

giardia presents __ weeks after exposure

A

1-3

33
Q

what organism is associated w. toxic megacolon

A

c.diff

34
Q

fever is rare with what waterborne pathogen

A

vibrio

35
Q

what strain of e.coli is associated w. HUS

A

0157:H7

36
Q

what foods is e.coli associated w. (3)

A

undercooked beef
unpasteurized milk/juice
cattle

37
Q

what foods is vibrio associated w. (2)

A

shellfish - raw oysters
water/poor sanitation

38
Q

how is shigella transmitted (3)

A

fecal oral/p2p
flies
inanimate objects

39
Q

what foods is salmonella associated w. (4)

A

meat
eggs
food handlers
reptiles

40
Q

what foods is campylobacter associated w. (3)

A

sausages
hard meats
undercooked chicken

41
Q

mc cause of epidemic waterborne diarrheal dz

A

giardia

42
Q

how is giardia transmitted

A

fecal oral

43
Q

4 rf for c.diff

A

abx
advanced age
previous hospitalization
nursing home

44
Q

tx for e.coli

A

supportive
abx if travelers diarrhea -> cipro

45
Q

what strain of e.coli is associated w. travelers diarrhea

A

enterotoxigenic E

NOT 0157:h7

46
Q

abx for vibrio

A

cipro or doxy

47
Q

tx for shigella

A

cipro
alt: bactrim/azithro

48
Q

abx for salmonella

A

cipro
alt: bactrim

49
Q

abx are rarely indicated for what 3 food borne pathogens

A

salmonella
vibrio
e.coli

hydration is main tx

50
Q

abx for campylobacter

A

cipro
alt: azithro

51
Q

abx for giardia (2)

A

metronidazole
tinidazole

52
Q

abx for c.diff (3)

A

oral vanco
fidaxamin
metro

53
Q

what pathogen is associated with dysentery

A

shigella

54
Q

what bacteria is associated w. cholera

A

vibrio

Pharmacotherapeutics - Final (6 decks)

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