Acute Cholecystitis Flashcards

1
Q

What is acute cholecystitis?

A

Chemical inflammation due to gallbladder obstruction

Involves bacterial growth from organisms like E. coli and others.

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2
Q

What are common bacteria involved in acute cholecystitis?

A
  • E. coli
  • Enterococci
  • Bacteroides fragilis
  • Clostridium (GRAM -ve)

These bacteria contribute to the inflammation and infection.

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3
Q

What are the symptoms of acute cholecystitis?

A
  • Dull pain in Epigastric/RUQ
  • Pain radiates to shoulder/back
  • Pain after meals
  • Constant pain worse on movement
  • Nausea/Vomiting
  • Sweating

Symptoms can vary in intensity and presentation.

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4
Q

What signs indicate acute cholecystitis?

A
  • Unwell appearance
  • Pyrexia (fever)
  • Tachycardia
  • RUQ tenderness
  • +++ Murphy’s Sign
  • Mass +/-

Murphy’s Sign is a specific sign for gallbladder inflammation.

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5
Q

What laboratory findings are expected in acute cholecystitis?

A
  • High CRP
  • Leukocytosis
  • Mildly elevated LFTs

These findings indicate inflammation and potential liver involvement.

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6
Q

What imaging techniques are used for diagnosing acute cholecystitis?

A

Ultrasound (USS) and Endoscopic Retrograde Cholangiopancreatography (ERCP)

USS shows gallstones, thick-walled GB, and fluid; ERCP visualizes the biliary tree.

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7
Q

What does the ultrasound reveal in acute cholecystitis?

A
  • Gallstones
  • Thick-walled GB
  • Fluid
  • Distended gallbladder
  • +++ Radiological Murphy’s sign

These findings help confirm the diagnosis.

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8
Q

What is the treatment for acute cholecystitis?

A
  • Supportive care: IV fluids, analgesia, antibiotics
  • May resolve on its own
  • Surgery: Cholecystectomy (Lap choli), drainage

Treatment depends on severity and patient’s condition.

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9
Q

What are the complications of acute cholecystitis?

A
  • Empyema - gallbladder fills with puss
  • Ischaemia
  • Perforation
  • Peritonitis
  • Sepsis

These complications result from untreated or severe inflammation.

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