Acute Care Exam 3 Flashcards
How are patients with ICP managed/treated?
- HOB > 30
- Control fever/BP
- SBP < 140
- Avoid hypotonics
What are the symptoms/clinical features of a TIA and what are the risk for stroke after TIA?
- onset of focal neuro Sx lasting < 24 hrs
- no objective evidence on brain studies
- risk of stroke after TIA is 2-17% w/in 90 days
What are the diet recommendations for stroke prevention?
- Mediterranean diet
- DASH diet
What are the effects of a PCA stroke?
- Right/Left homonymous hemianopia
- Alexia w/out agraphia
- Possible aphasia
- Contralateral hemisensory
How is HLD and stroke related and what Rx/dose is used in prevention?
- Stroke risk r/t LDL levels
- Lipitor 80 mg
What are the TPA contraindications r/t CT scans?
Blood on CT (light color)
What are the stroke center levels and some key differences between them?
- primary stroke center:
- most cases of ischemic stroke
- not req’d to have cath services
- not req’d to have a separate unit
- access to neurosurg w/in 2 hrs
- comprehensive stroke center:
- all types of stroke
- 24/7 cath services
- have separate neuro ICU
- 24/7 on site neurosurg
What are the AHA recommendations for exercise for stroke prevention?
- any exercise reduces stroke risk
- AHA:
- 30 mins mod activity 5 d/wk or
- 25 mins vigorous activity 3 d/wk
What is the CURB-65 and what are its components?
- Scoring system to help diagnose CAP
- Components (1 pt each):
- C - confusion
- U - urea > 7 mmol/L
- R - RR > 30
- B - SBP < 90 mmHg or DBP < 60 mmHg
- 65 - age > 65
- 0-1 = low risk, 2 = probable, 3-5 = hosp visit
What are the diagnostic features of a hemorrhagic stroke?
- ICH score
- CT (blood is light)
- MRI (blood is dark)
- Seizures
- Neurosurgery:
- EVD
- evacuation of blood
- increased ICP (>20 mmHg)
What are the cryptogenic stroke associated risk factors?
- arterial dissection, arteriopathy
- cerebral sinus venous thrombosis
- autoimmune Dz and genetic factors
- infxn
- hypercoaguability Dz
What are the effects of a Right MCA stroke?
- Left sided deficits
- Left hemiplegia/sensory loss
- Left homonymous hemianopia
- Left hemi-neglect
- Right gaze preference
How is VAP prevented?
- HOB elevated
- handwashing
- chlorhexidine gluconate oral rinse
- cont removal of subglottic secretions
What are the prevention protocols for CLABSI?
- Hand hygiene
- optimal insertion site
- prep skin w/ 2% CH or 70% isopropyl alcohol
- maximal sterile barrier and intact dressing
- daily review of necessity and early removal (5 day max)
What are the risk factors for hemorrhagic stroke?
- HTN
- increased age
- cerebral amyloid angiopathy
- antithrombotic therapy
- increased EtOH and/or drug abuse
What differential diagnoses should be considered if CAUTI suspected?
- pyelonephritis
- sepsis
- bactermia
- PNA
- skin/soft tissue infxn
What are the Sx of a hemorrhagic stroke?
- stroke Sx w/ HA
- HA usually intense, extremely painful
- vomiting
- decreased LOC
What are the TPA contraindications r/t Rx history and what Rxs are ok?
- Currently on:
- Anticoags
- Eliquis, Xeralto, Pradaxa, full dose LMWH or Heparin gtt
- Anticoags
- ASA and Plavix are ok
What is the treatment for VAP?
- initially treated with broad specturm ABX
- specturm should be subsequently narrowed
- pathogen may influence treatment
- usually 7 days
What neurotransmitters increase pain?
- bradykinins and tacyhkinins (sub-P, neurokinin-A)
- cations and free radicals
- histamine and serotonin
- prostanoids (PTG, leukotrienes)
- purines (adenosine, ATP)
What are the characteristics and treatment of neuropathic pain?
- characteristics:
- pain from dmg nerve endings that result in abnormal signal processing. Pain sensation serves to purpose
- treatment:
- gabapentin 100 mg 1-3x/day, titrate up to 1800 mg/day
- lyrica 25-100 mg up to q 8hr
- cymbalta (duloxetine)
- tapering req’d at end of treatment
What is the diagnostic criteria for HAP?
- arises 48 hrs or more after hospital admission not incubating at time of admission
What is the treatment fo COVID-19?
- no approved FDA treatment, get it and ur ded
- supportive mgmt of complications
What is the A1c goal for stroke prevention?
< 7%
What is important in a migraine assessment and what is included in prevention, workup, and treatment?
- most important: history, history, history
- complicated Dx of exclusion
- status migrainosus (HA > 72 hrs)
- Treatment:
- NSAIDs, neuroleptics, triptans, ergot, alkaloids, opioids
- PPX:
- propranolol, topamax, TCA, depakote
- Must treat in pregnancy
- r/t eclampsia; magnesium used in Tx
What are the effects of an ACA stroke?
- Leg weakness
- Leg sensory loss
- Behavior abnormalities (Frontal Lobe)
- Transcortical aphasia (Left ACA)
- Left hemi-neglect (Right ACA)
How are obesity, smoking, and OSA r/t storke prevention?
- obesity and smoking increases risk for stroke
- OSA is an independent risk factor for storke
What are the S/Sx of SIRS?
- Temp > 38 or < 36
- HR > 90
- RR > 20 or PaCO2 < 32
- WBC > 12 or < 4 or bandemia present (> 10%)
What is the most common CAUTI pathogen?
E. coli
What is the TOAST criteria and what is it comprised of?
- classification system for ischemic stroke into 5 subtypes
- types:
- large artery atherosclerosis
- cardioembolism
- small vessel occulusion
- stroke of other determined etiology
- stroke of undertermined etiology
What are the causes/contributing factors to an embolic stroke?
- embolism
- atherosclerosis
- inflammation
What is the general treatment for CAUTI?
ABX for 7-14 days
How do older patients present with CAUTI?
- AMS
- altered appetite
What are the risk factors for developing VAP?
- duration of intubation or nasogatric intubation
- large vol aspiration or chronic lung Dz
- depressed LOC
- supine
- thoracoabdominal surgery
- prior ABX
What are the clinical features of sepsis?
- mycardial depression
- altered vasculature and organ perfusion
- imbalance of O2 delivery and comsuption
- metabolic (lactic) acidosis
What are the TPA contraindications r/t vital signs and lab values?
- glucose < 50 or > 400
- BP > 185/110
- PLT < 100,000
- INR > 1.7 and on warfarin
What substances inhibit pain?
- endogenous opioid peptides
- enkalphins - spinal cord/brainstem
- triggered by serotinin
- beta-endorphines - hypothalamus/pituitary
- most like morphine
- dynorphins - released by spinal cord/brainstem
- 200x stronger vs morphine
What is the BP goal for stroke prevention with HTN?
- <140/90
- w/ DM <130/90
What are the TPA contraindications r/t history?
- Basically are you bleeding now or bled a lot before
- Recent
- acute stroke
- major surgery (last 2 wks)
- or current GI/GU bleed
- major head trauma
- Hx of intracranial hemorrhage
- Recent
What are the effects of a Left MCA stroke?
- Right sided deficits and language impairments
- Right hemiplegia/sensory loss
- Expressive aphasia (Broca’s)
- Receptive aphasia (Wernicke’s)
- Right homonymous hemianopia
What the testing/lab abnormalities r/t SARS-CoV-2?
- lymphopenia (most common)
- neutrophilia ↑
- serum alanine aminotransferase ↑
- aspartate aminotransferase ↑
- lactate dehydrogenase ↑
- CRP ↑
- ferritin ↑
- procalcitonin ↑ (in ICU usually)
- elevated D-dimer
- ↑ risk of mortality
What is included in the NIH stroke scale and what does the scoring mean?
- 11 components that grade stroke deficits
- 0-42 points
- Higher score = more stroke deficits