Acute arterial occlusion Emboli Flashcards
symptoms of Acute Arterial Occlusion
Abrupt attack of excruciating pain
Numbness, coldness, tingling
After 6 hrs muscle undergo intensive contractures and swell
After 10 hrs skin have irreversible changes
6 P’s of ischemia secondary to acute arterial occlusion
Pulsessness pain pallor paresthesias (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin ) poikliothermia palor
What do you find on a physical exam of a pt Acute Arterial Occlusion ?
Pallor due to spastic reaction of arterial tree
Over 12 hrs and limb becomes cyanotic and mottled
Stasis
Pulses absent distal to occlusion
Area of temp demarcation
loss of light touch and position sense
Distension of superficial veins
Differential diagnosis of Acute Arterial Occlusion ?
Iliofemoral thrombophlebitis
Arterial spams
Pathophysiologic factors in Acute Arterial Occlusion
Size of the obstructed artery Adequacy of collateral circulation Extent of occluded lesion Arteriospasm Fragmentation of thrombus/Emboli Secondary venous thrombosis
perfusion in Acute Arterial Occlusion
BLOOD BECOMES STAGNANT IN EXTREMITY
- Increase oxygen free radicals
- Damage to surrounding tissues and causes necrosis
- systemic circulation becomes overload with lactate , K, myoglobin and toxins
- Urine is overloaded with alkaline products
- Leads to CV depression and renal failure
examples of O2 free radicals
xantine oxidase
H2O2
O2(superoxide)
OH ( hyroxyl radical)
surgical treatment for Acute Arterial Occlusion ?
- Embolectomy
- Bypass or graft
- Thrombolysis
Acute Emboli
HIgh mortality rate
Acute Thrombotic occlusion
High limb loss rate
Embolo after acute MI
40% mortality rate
Emboli with atrial fib
9%
Embolus can be
Thrombus Fat Air Vegetation Atheromatous material
pathogenesis of embolus
Fracture Trauma Surgery Aniography Anticoagulants Cardian catheterization Angioplasty
Embolus affect
arteries and veins