Acute and Chronic Inflammatory GI Disease

Question 1

What is the most common symptom of GI inflammation?

Answer 1

diarrhoea

Question 2

What is the difference between acute infectious diarrhoea and chronic diarrhoea?

Answer 2

• chronic is longer than 2 weeks

- acute infectious is less than 2 weeks

Question 3

What can cause the acute infectious form?

Answer 3

• emotional stress
• food intolerance
• organic substances
• drugs and infectious agents

Question 4

What are the 6 categories of chronic diarrhoea?

Answer 4

osmotic
secretory
inflammatory
malabsorptive
chronic infections
motility disorders diarrhoea

Question 5

What is a sign of inflammation?

Answer 5

blood in the stool

Question 6

What areas does ulcerative colitis affect?

Answer 6

• begins in the rectum and may extend continuously to involve the entire colon
• usually terminal ileum

Question 7

What areas does Crohn’s disease include?

Answer 7

• most commonly involves the end of the small intestine and beginning of colon
• may affect any other part of the GI tract
• patchy pattern

Question 8

Whats the difference between Crohn’s and ulcerative colitis?

Answer 8

• ulcerative colitis affects mucus layer

- Crohn’s disease affects all layers

Question 9

What us a granuloma?

Answer 9

when the immune cells surround something

Question 10

In Crohn’s disease, what does mucosal ulceration lead to?

Answer 10

fibrosis, stricturing, fistula formation

Question 11

What types of investigations do you carry out for IBD?

Answer 11

• history and examination
• bloods (full blood count, urea and electrolytes, liver function tests, C reactive protein)
• stool (c.difficile, other pathogens)
• abdominal x-ray
• sigmoidscopy
• colonoscopy
• small bowel imaging
• histology

Question 12

How do you manage IBD?

Answer 12

usually treat with steroids (other methods on slides)