Acute and Chronic Inflammation L3 Flashcards
Inflammation definition
Body’s response to injury or infection using different types of cells
What are the two traditional splits of inflammation?
Acute
Chronic
More “sense” splits of inflammation / new split of inflammation
Neutrophil-mediated inflammation Macrophages/lymphocyte mediated
inflammation
What are neutrophil polymorphs and where are they made?
White blood cells
Bone marrow
What is the lifespan of neutrophil polymorphs?
2-3 days
Why are they called polymorphs?
Have a polylobed nucleus
Polymorphs can ___ debris and bacteria (by _______) and contain bags of enzymes (known as ______) which can be used to ____ and ____ phagocytosed bacteria
Eat
Phagocytosis
lysosomes
Kill
Digest
What are the first cells to arrive at the site of an acute inflammation?
Neutrophils
Neutrophils often ___ at the site of inflammation and
are themselves ____________ by __________
Die
Phagocytosed
Macrophages