Activity 8 - Structural Activity Relationship Of Beta-Lactam Antibiotics

Question 1

It refers to what the body does to a drug.

Answer 1

Pharmacokinetics

Question 2

It refers to the movement of drug into, through and out of the body- the time course of its absorption, bioavailability, distribution, metabolism and excretion.

Answer 2

Pharmacokinetics

Question 3

It refers to what the drug does to the body.

Answer 3

Pharmacodynamics

Question 4

It involves the receptor binding, post receptor effects, and chemical interactions.

Answer 4

Pharmacodynamics

Question 5

The study of action or effects of drugs on the body/living organism.

Answer 5

Pharmacodynamics

Question 6

Capable of inhibiting the growth or reproduction of bacteria.

Answer 6

Bacteriostatic

Question 7

Agents that kill bacteria.

Answer 7

Bactericidal

Question 8

Destruction or decomposition, as of a cell or other substances under the influence of a specific agent.

Answer 8

Lysis

Question 9

The time it takes for a substance to lose half of its pharmacological, physiologic or radiological activity.

Answer 9

Half-life

Question 10

4th generation cephalosporins

Answer 10

1. Cefepime
2. Cefpirome
3. Cefoselis

Question 11

For gram positive bacteria

Answer 11

1st generation cephalosporins

Question 12

For gram negative bacteria

Answer 12

2nd generation cephalosporins

Question 13

For gram negative and penicillinase-resistant bacteria

Answer 13

3rd generation cephalosporins

Question 14

For both gram positive and negative bacteria

Answer 14

4th generation cephalosporins

Question 15

Side effect of penicillins and cephalosporins

Answer 15

Hypersensitivity

Question 16

Ticarcillin is paired with what beta-lactamase inhibitor?

Answer 16

Clavulanic acid

Question 17

What process in bacteria does penicillins and cephalosporins interrupt?

Answer 17

Peptidoglycan synthesis

Question 18

Medicines that cannot be taken with penicillins:

Answer 18

1. Allopurinol
2. Oral contraceptives
3. Methotrexate