Active learning 1-5

Question 1

Ectopic signalling sources are useful to determine:
A - cell fate
B - Induction
C - Requirement
D - Cell proliferation
E - All of the above

Answer 1

B- induction

Question 2

Which phrase best describes cell committment?

A. a labelled cell that always becomes a specific cell type
B. induction by cell signalling after transplantation
C a cell that has the same fate even when moved to another location
D. cell proliferation that is only activated in the early embryo
E. none of the above

Answer 2

C - a cell that has the same fate even when moved to another location

Question 3

The mouse model has which of the following advantages?

A. mammal
B. rapid generation time
C. inbred strains
D. embryonic stem cell culture
E. all of the above

Answer 3

E - all of the above

Question 4

All vertebrates have:

A. an endoskeleton
B. lungs
C. inbred strains
D. embryonic stem cell culture
E. all of the above

Answer 4

A - an endoskeleton

Question 5

The ectoderm gives rise to

A. neurons
B. glia
C. epidermis
D. pigment cells
E. all of the above

Answer 5

E - all of the above

Question 6

The mitotic cycle has the following order

A. M->G1->G2->S
B. G1->S->G2->M
C. M->S->G1->G2
D. G1->G2->S->M
E. none of the above

Answer 6

B - G1->S->G2->M

Question 7

During limb development, FGF genes

A. are expressed in the ZPA
B. pattern the proximal/distal axis of the limb
C. specify digit identity
D. promote growth of the limb
E. all of the above

Answer 7

D - promote growth of the limb

Question 8

A key concept for morphogen activity is

A. the anterior/posterior axis
B. a concentration gradient
C. cell transplantation
D. cell proliferation
E. all of the above

Answer 8

B - a concentration gradient

Question 9

Differentiation involves

A. cell type specific transcription factors
B. signalling
C. expression of a subset of the genes in the genome
D. terminal differentiation
E. all of the above

Answer 9

E - all of the above

Question 10

Which of these statements is not true?

A. muscle fibres form from mesodermal progenetors
B. myoD is sufficient to induce muscle differentiation in fibroblasts
C. myoD is required for muscle specification
D. myogenin is involved with muscle fibre maturation
E. mrf5 activates myf5

Answer 10

C - myoD is required for muscle specification

Question 11

Dominant negative mutations are also known as

A. hypomorphic
B. hypermorphic
C. amorphic
D. haplosufficient
E. none of the above

Answer 11

E - none of the above

Question 12

Gene names should be

A. written in bold
B. italicised
C. written in lowercase
D. underlined
E. written as superscript

Answer 12

B - italicised