Actin Flashcards
1
Q
Where is actin found in a cell?
A
Right under the membrane mostly, but also all throughout.
2
Q
Is actin rigid or elastic?
A
Actin is compressionably rigid but laterally elastic. Formed into bundles to give lateral rigidity.
3
Q
What does actin control?
A
Cell structure me shape Cell migration and motility Cell adhesion Tension forces Endocytosis Cell division (cytokinesis)
4
Q
Actin Structure
A
+ end “barbed”
–end “pointed”
Filaments are 2 monomers wide.
5
Q
What is the rate limiting step of actin polymerization and what causes the plateau?
A
Nucleation and treadmilling
6
Q
Nucleation
A
4 monomers form a reframed
