ACS Notes

Question 1

HBr
——->
Peroxides (R-O-O-R)

Answer 1

antimarkov- add to the least stable positions

Question 2

BH3, THF
—->
NaOH H2O2

Answer 2

antimarkov-antimarkov- add to the least stable positions

Question 3

Hg(OAc)2/H2O/NaBH4

Answer 3

does not cause a hydride shift, forms a epoxide intermediate

Question 4

O3/Me/S
the ozone

Answer 4

always makes a ketone and aldehyde!!!!!!!

Question 5

KMnO4/OH with heat

Answer 5

always make COOH and ketone!

Question 6

NaBH4 not as strong, selective

Answer 6

converts ketones and aldehydes to alcohols

Question 7

DiBAI-H

Answer 7

reduces esters to aldehyde

Question 8

LiAlH4/THF

Answer 8

reduced ketones, COOH to alcohols

Question 9

PCC

Answer 9

oxidizing agent makes 1* alcohols to aldehyde
and 2* into Ketone

Question 10

CrO3/H2SO4/H2O

Answer 10

converts 1* alcohol to COOH

Question 11

KMnO4/OH? H*

Answer 11

converts Alcohols to COOH or Ketone, but also 2x bonds to COOH

Question 12

LiAIH(OBU)

Answer 12

COOH and dervi(COO) into amldehyde only!!!!!!AHHHAAHAHA

Question 13

TsCl is used for

Answer 13

making OH a good leaving group and making esters! and works as a protecting group

Question 14

KMnO4 , OH, heat can..

Answer 14

cleave the 2x bond

Question 15

what type of additions are epoxides

Answer 15

they are syn addition, meaning same side

Question 16

ClsiMe3 is also

Answer 16

a alcohol protecting group

Question 17

sp3 for NMR

Answer 17

1ppm

Question 18

H Bonded to a pie system (2x bond)

Answer 18

2ppm

Question 19

H bonded to an O

Answer 19

3-4 ppm

Question 20

Halogens

Answer 20

4 ppm

Question 21

aldehyde

Answer 21

10 ppm

Question 22

carboxylic acid

Answer 22

11-12 ppm

Question 23

aromatic

Answer 23

1500

Question 24

3x bonds and CN

Answer 24

2100

Question 24

sp2 cx( single bonds)

Answer 24

3100-3000

Question 25

what reagents is used to carry out diels alder

Answer 25

heat needs to be inovolved to drive the rxn forward

Question 26

Zn(Hg) con do to cooh derv.

Answer 26

reduces( rids of 2x bonds)

Question 27

what does HNO3/H2SO4 do

Answer 27

Makes NO2

Question 28

NH2 undergo with NaNO2

Answer 28

N—N(3x bonds)

Question 29

N—N(3xbonds) with H2PO2

Answer 29

Benzene

Question 30

lindar

Question 31

what is more stable 1,4 or 1,2 addition

Answer 31

1,4 - thermodynamic favored and stable due to charge stability

Question 32

1,4 is conjugated and is attacked

Answer 32

at B positioning

Question 33

1, 2 are direct and is attacked

Answer 33

a alpha positioning

Question 34

Reversible reagents

Answer 34

OH, RO, H2N, R2N, Cl, Br, I, CN, COOH. LiCu

Question 35

irreversible reagents

Answer 35

MgBr-R, R-Li, LiAlH4, NaH4, witting(C-P)

Question 36

O3/H20

Answer 36

makes 3x bonds into 2 COOH

Question 37

HCI/Zn rids of

Answer 37

COOH