ACOG Qs Flashcards
describe screening for gestational diabetes
- done at 24-28 wks in women w/o risk factors
- done at 1st prenatal appt for women w/risk factors (previous hx gestational DM, obese bmi>30, glucose metabolism issues
- screen with 50g oral glucose, diagnostic test w/ 75 g 2 hr oral glucose
OR
-75g 2 hour oral glucose challenge
def of labor
onset of contractions+cervical effacement and dilation
Latent phase Active phase
latent phase: 0 cm to 6 cm dilated active phase: 6 cm to 10 cm dilated
define the diagnosis of preeclampsia
-htn after 20 wks gestation -BP>140/90 2 times >4 hours apart -proteinuria: >300 mg/24 hour urine, protein/Cr>0.3, urine dipstick +1 OR -systemic signs: platelets <100K, Cr>1.1, LFTS 2x normal, pulmonary edema, visual or cerebral signs
pregnancy risk factors for developing preeclampsia
1-preeclampsia in prior pregnancy first pregnancy multiple gestation preeclampsia in 1st degree relative
what maternal past medical history increases the risk for preeclampsia?
renal disease chronic htn hypercoagulability diabetes mellitus obesity >40 years old lupus
complications of preeclampsia
-eclampsia-development of seizures -HELLP syndrome: hemolysis, elevate liver enzymes, low platelets (epigastric pain, malaise, nausea, headache in 3rd trimester) -placental abruption -stroke -renal damage -liver damage -ARDS
normal fetal heart rate
110-160 bpm
preeclamptic woman with 3rd trimester vaginal bleeding is likely due to?
placental abruption -signs on fetal heart tracing:tachycardia, sinusoidal heart rate pattern)
what occurs at these different MgSO4 levels in mEq/L 4-7 7-10 10-15 >15
4-7: therapeutic level 7-10: loss of DTRs (deep tendon reflexes) 10-15: respiratory depression (<12 breathes/min) >15: cardiac arrest
1st trimester vaginal bleeding differentials
what are the 3 cardinal signs of an ectopic pregnancy
amenorrhea
vaginal bleeding (1st trimester)
abdominal pain
gardnerella
- signs
- RX
gray white discharge
foul odor
ph>4.5
RX: metronidazole or clindamycin
what maternal medical condition is assoc with the highest rate of mortality
pulmonary htn, eisenmengers (R–>L shunt)
what is the management for pregnant women with cardiac diseases
- discuss terminating the pregnancy
- labor and delivery management
–early epidural to minimize cardiac stress
–forceps or vacuum assisted vaginal delivery to prevent valsalva while pushing
–fluid management: bc postpartum there’s massive venous return as vena cava is no longer impinged
management for renal disease in pregnant women
1st line-recommend termination of pregnancy
-inc risk of preeclampsia, gestational diabetes, htn
- evaluate for preeclampsia via
- baseline level of proteinuria (bc renal disease can cause proteinuria) vs new onset proteinuria
- uric acid levels: dec renal clearance–>buildup
- BP inc of > 30/15
pregnant woman experiences tachycardia, bulging eyes, diaphoresis…diagosis..RX
thyroid storm
- RX
- PTU/Methimazole-block production of T4, PTU also (-) peripheral conversion of T4–>T3
- B blockers-to slow HR
- dexamethasone (-) thryoid hormone production and periheral T4–>T3 conversion
- antipyretics
*
Pregnany woman with asthma, what should be given for
- mild asthma
- moderate asthma
- acute setting
mild asthma-SABA as needed
moderate-if SABA use is >2x per week give SABA+inhaled corticosteroids, cromolyn (mast cell stabilizer) if refractory
acute setting-systemic steroids (oral), terbutaline (B2 agonist)
can radioactive I131 be given to a pregnant woman in thyroid storm
No-bc it can cross the placenta causing neonatal hypothyroidism
pregnant woman with lupus. what are the complications
placental thrombosis->2nd trimester fetal loss
neonatal lupus-malar rash, heart block
***lupus can resemble preeclampsia
***perform serial fetal echos to determine risk of fetal heart block
what meds should be given to pregnant women with lupus
lovenox or heparin-to prevent placental thrombosis
aspirin-to prevent thrombosis
steroids-bc lupus is an autoimmune disease
for refractory lupus-cyclophosphamide
you suspect postpartum depression in a woman. what is your next step.
-
- evaluate for harm to self or baby
- prescribe an SSRI
SSRIs during pregnancy
- never give an SSRI to a person with a fam hx or diagnosis of Bipolar disorder bc it could provoke mania
- paroxetine contraindicated-causes pulmonary htn and cardiac malformations
name the different types of herpes infections
initial primary infection
-1st infection, symptoms severe, antibody (-)
initial non-primary infection
-1st infection, moderate severity, antibody (+)
recurrent infection
-recurrent symptoms, mild symptoms, antibody (+)
asymptomatic infection
at what wk do we induce women for elective c-sections and why
after 39 wks-to prevent prematurity
is vaginal bleeding in a perimenopausal woman with menopause symptoms a contraindication for hormone replacement therapy?
yes
-abnormal vaginal bleeding can be a sign of endometrial cancer, and HRT (estrogen) can worsen it. Must either perform a biopsy or US with endometrial stripe <4 mm to ok giving HRT
what amt of Ca is appropriate to give a postmenopausal woman
1200 mg Ca total
-With inc age there’s a decrease in bioavailable vit D, which dec Ca absorption
-
risks assoc with taking HRT (estrogen +progestin)
protective effects of HRT
- inc risk of breast cancer
- CV event: thromboembolism, DVT, PE, stroke
protective effects: dec risk of colon cancer and fractures
risks assoc with taking estrogen only for menopause symptoms
-estrogen alone causes inc risk of cv events (stroke, thromboembolism)
give estrogen to post menopausal women w/o a uterus
give estrogen+progestin to women with a uterus-to prevent endometrial hyperplasia
contraindications to taking hormone replacement therapy
Contraindications
Undiagnosed vaginal bleeding-could be endometrial cancer
Pregnancy
Breast cancer/endometrial cancer
Chronic liver disease
Hyperlipidemia
Recent DVT/stroke
Coronary artery disease
Recommendations of hormone replacement therapy
- <60 yrs, within 10 yrs of menopause
- only treat HRT with the smallest effect dose that affects daily life
- only treat if the pt has symptoms affect daily living, if they don’t then do expectant management (watch & wait)
for hormone replacement therapy
- estrogen only inc risk of
- estrogen+progestin inc risk of
estrogen only-no inc risk of breast cancer, inc risk of CV events
estrogen+progestin: breast cancer (so progestins are the culprits)
describe the source of estrogen pre and post menopausal
premenopause-ovaries
postmenopause-ovarian androgens converted in the periphery (fat tissue)
- after menopause ovaries stop making estrogen, but estrogen continues to be high bc ovaries make androgens that are converted into estrone by fat tissue
- body weight is directly proportional to estrogen levels
most common symptom of gestational trophoblastic diseases?
Vaginal bleeding
a woman has a molar pregnancy removed, her b-hcg after 2 months falls then rises again. Next step
-redo b-hcg 48 hrs later to determine the rate of rise. you don’t know if this is persistent trohoblastic disease or normal
a woman w likely molar pregnancy, if you suspect metastatic choriocarcinoma what is the next step
- do not biopsy bc choriocarcinoma is too vascular
- instead, do a chest xray (lung mets), liver labs (liver mets), brain mri (brain mets) before surgical D&C in case you need to
on pelvic exam you find a fleshy mass w/a stalk off the cervix. next step
polypectomy-you can confirm on pelvic exam a polyp. colposcopy is not done for polyps, it’s done for suspicion of cervical dysplasia and cancer