Acneiform Eruptions Flashcards
What is the medical name for common acne?
Acne vulgaris
How does the prevalence of acne change over time?
Nearly 90% of teenagers have acne, by age 40 only 1% of men and 5% of woman still have lesions
Who is at increased risk of acne?
- XYY genotype
- Polycystic ovarian syndrome
- Hyperandrogenism
- Hypercortisolism
Describe the pathogenesis of acne?
1) Early comedone
2) Later comedone
3) Inflammatory papule/pustule
4) Nodule/cyst
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What are the different severities of acne?
Mild acne
Moderate acne
Severe acne
When is acne considered to be mild acne?
Open and closed comedones (skin coloured, small bumps (papules)):
- <20 comedowns
- <15 inflammatory lesions
- Or total lesions count <30
Is mild acne inflammatory or non-inflammatory?
Non-inflammatory
What are closed comedones known as?
Whiteheads
What are open comedones known as?
Blackheads
Why does black discolouration occur in open comedones?
- Black discolouration due to melanin deposition and lipid oxidation
Is moderate acne inflammatory lesions or non-inflammatory lesions?
- Papules, pustules, nodules and cysts
- 20-100 comedones
- 15-50 inflammatory lesions
- Or total lesion count 30-125
When is acne considered to be moderate acne?
- Papules, pustules, nodules and cysts
- 20-100 comedones
- 15-50 inflammatory lesions
- Or total lesion count 30-125
When is acne conisdered to be severe acne?
- >5 pseudocysts
- Total comedo count>100
- Total inflammatory count >50
- Or total lesion count >125
What are the long-term impacts of severe acne?
Causes permanent scaring and post inflammatory pigmentation
What are some different varients of acne?
- Acne fulminans
- Drug induced acne
- Acne excoriee
What is acne fulminans?
Most severe form of cystic acne
Characterised by abrupt onset of nodular and suppurative acne with systemic manifestations:
Fever, artralgias, myalgias, hepatosplenomegaly