Acne Flashcards
What causes increased sebum production?
Sebaceous gland hyperactivity due to increased androgen production
Sebum release is influenced by?
IL-1 by Follicular Keratinocytes
Follicular epithelial hyperproliferation is in response to?
IL-1
What organism causes acne?
Propionibacterium acnes
What causes infundibular rupture?
Epidermal Growth Factor
[Treatment]
Follicular Hyperkeratinization
Comedolytic/Keratolytic Agents
Topical Retinoids
Salicyclic Acid
[Treatment]
Sebum Production
Serostatic
Oral isotretinoin
OC Pills
Anti-Androgens
[Treatment]
P. acnes proliferation
Tetracycline
Clindamycin
Benzoyl Peroxide
[Treatment]
Inflammation
Intralesional Steroids
Oral Steroids (SEVERE ONLY)
Topical Isotretinoin
[Mechanism of Action]
Benzoyl Peroxide
Release of oxygen inside and reduces inflammation and controls P. acne proliferation
What kind of a diet increases the incidence of acne?
High glycemic index diet
What specific food is linked to increase of acne?
Milk
Scrub or not to scrub?
No, it will cause trauma