Acne Flashcards

1
Q

What causes increased sebum production?

A

Sebaceous gland hyperactivity due to increased androgen production

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2
Q

Sebum release is influenced by?

A

IL-1 by Follicular Keratinocytes

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3
Q

Follicular epithelial hyperproliferation is in response to?

A

IL-1

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4
Q

What organism causes acne?

A

Propionibacterium acnes

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5
Q

What causes infundibular rupture?

A

Epidermal Growth Factor

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6
Q

[Treatment]

Follicular Hyperkeratinization

A

Comedolytic/Keratolytic Agents

Topical Retinoids
Salicyclic Acid

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7
Q

[Treatment]

Sebum Production

A

Serostatic

Oral isotretinoin
OC Pills
Anti-Androgens

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8
Q

[Treatment]

P. acnes proliferation

A

Tetracycline
Clindamycin
Benzoyl Peroxide

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9
Q

[Treatment]

Inflammation

A

Intralesional Steroids
Oral Steroids (SEVERE ONLY)
Topical Isotretinoin

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10
Q

[Mechanism of Action]

Benzoyl Peroxide

A

Release of oxygen inside and reduces inflammation and controls P. acne proliferation

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11
Q

What kind of a diet increases the incidence of acne?

A

High glycemic index diet

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12
Q

What specific food is linked to increase of acne?

A

Milk

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13
Q

Scrub or not to scrub?

A

No, it will cause trauma

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