Acne Flashcards
Is there a cure for acne?
No, there is no known cure for acne, but there are treatments to keep it under control.
Define acne
An inflammatory disease of the sebaceous glands. Another name for acne is “retention hyperkeratosis”. (Retention of dead skin cells and rampant proliferation of additional cells).
what is another name for a pore?
Follicle (these two words can be used interchangeably)
Describe a pore / follicle
A follicle is the tiny structure that opens onto the skin’s surface whether or not a hair grows out of it or not. A developing follicle has two choices: it will either produce a hair (a hair follicle) or it will predominantly produce oil (sebaceous follicle).
if a baby is genetically ance-prone and has acne flares on the face as a baby
neonatal acne
what hormone stimulates the development of our sebaceous follicles and their attached oil glands?
Testosterone
what is sebum?
sebum is the skin oil produced by the sebaceous glands. sebum is a complex mixture of lipids (fats)
what is anaerobic bacteria
bacteria that grows without the presence of oxygen and feeds off of the triglycerides produced by our sebaceous glands. this bacteria flourishes in the follicles.
why does acne appear on different areas of the body at different times?
not all sebaceous follicles mature at the same time, instead they mature and begin producing oil in a progression that moves across the face and body like a wave.
- central forehead, nose and central chin (12-14)
- cheeks, upper back and chest (15-16)
- jaw line, upper neck, low back (18-19)
Describe retention hyperkeratosis
the stratum corneum sloughs off a layer of dead skin cells each day, inside the pore as well. the keratin loaded skin cells (keratinocytes) are produced at an abnormally rapid rate, 4-5x’s more in the acne affected pore. in the process of acne, these dead skin cells begin to stick togeter and form a mass (an impaction) down inside the follicle. dead skin cells, sebum, rudimentary hair, bacteria and their by-products are retained inside the pore.
how does stress effect acne?
stress activates the adrenal glands to produce extra hormones which eventually results in flare ups in the acne prone pores. this is more common in women because they produce most of their male hormones in the adrenal glands whereas men produce it mostly in the testes.
another way stress effects acne is by weakening the body, causing healing of the lesion to be interrupted.
what are some of the factors that contribute to acne from the outside in
climate
pressure or friction
picking
industrial chemicals & oils
what are some factors that contribute to acne from the inside out?
iodides/iodines
diet - food containing hormones (peanut, corn & wheat germ oils)
steroid drugs (systemic) used for RA, kidney disease, etc.
steroid drugs (topical) used for acne rosacea
testosterone injections or pills (steroids for athletes)
danazol or danocrine (med. for endometriosis, similar to testosterone)
lithium (for depression)
dilantin (for epilepsy or anti-convulsions)
marijuana
androgens?
androgen is a general term for male hormones. the main one is testosterone which is tied to acne.
how do male hormones effect acne?
it causes flare ups by stimulating greater production of sebum.
what usually happens when taking estrogen dominant birth control pills?
flooding the body with extra estrogen clears acne for many acne-prone women by shutting down testosterone production in the ovaries.
when do most acne-prone women see post pregnancy acne flare?
acne often flares 90 days or so after pregnancy, and can also happen when getting off of birth control pills (from hormonal fluctuation)