Acne Flashcards

0
Q

Is there a cure for acne?

A

No, there is no known cure for acne, but there are treatments to keep it under control.

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1
Q

Define acne

A

An inflammatory disease of the sebaceous glands. Another name for acne is “retention hyperkeratosis”. (Retention of dead skin cells and rampant proliferation of additional cells).

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2
Q

what is another name for a pore?

A

Follicle (these two words can be used interchangeably)

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3
Q

Describe a pore / follicle

A

A follicle is the tiny structure that opens onto the skin’s surface whether or not a hair grows out of it or not. A developing follicle has two choices: it will either produce a hair (a hair follicle) or it will predominantly produce oil (sebaceous follicle).

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4
Q

if a baby is genetically ance-prone and has acne flares on the face as a baby

A

neonatal acne

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5
Q

what hormone stimulates the development of our sebaceous follicles and their attached oil glands?

A

Testosterone

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6
Q

what is sebum?

A

sebum is the skin oil produced by the sebaceous glands. sebum is a complex mixture of lipids (fats)

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7
Q

what is anaerobic bacteria

A

bacteria that grows without the presence of oxygen and feeds off of the triglycerides produced by our sebaceous glands. this bacteria flourishes in the follicles.

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8
Q

why does acne appear on different areas of the body at different times?

A

not all sebaceous follicles mature at the same time, instead they mature and begin producing oil in a progression that moves across the face and body like a wave.

  1. central forehead, nose and central chin (12-14)
  2. cheeks, upper back and chest (15-16)
  3. jaw line, upper neck, low back (18-19)
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9
Q

Describe retention hyperkeratosis

A

the stratum corneum sloughs off a layer of dead skin cells each day, inside the pore as well. the keratin loaded skin cells (keratinocytes) are produced at an abnormally rapid rate, 4-5x’s more in the acne affected pore. in the process of acne, these dead skin cells begin to stick togeter and form a mass (an impaction) down inside the follicle. dead skin cells, sebum, rudimentary hair, bacteria and their by-products are retained inside the pore.

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10
Q

how does stress effect acne?

A

stress activates the adrenal glands to produce extra hormones which eventually results in flare ups in the acne prone pores. this is more common in women because they produce most of their male hormones in the adrenal glands whereas men produce it mostly in the testes.

another way stress effects acne is by weakening the body, causing healing of the lesion to be interrupted.

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11
Q

what are some of the factors that contribute to acne from the outside in

A

climate
pressure or friction
picking
industrial chemicals & oils

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12
Q

what are some factors that contribute to acne from the inside out?

A

iodides/iodines
diet - food containing hormones (peanut, corn & wheat germ oils)
steroid drugs (systemic) used for RA, kidney disease, etc.
steroid drugs (topical) used for acne rosacea
testosterone injections or pills (steroids for athletes)
danazol or danocrine (med. for endometriosis, similar to testosterone)
lithium (for depression)
dilantin (for epilepsy or anti-convulsions)
marijuana

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13
Q

androgens?

A

androgen is a general term for male hormones. the main one is testosterone which is tied to acne.

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14
Q

how do male hormones effect acne?

A

it causes flare ups by stimulating greater production of sebum.

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15
Q

what usually happens when taking estrogen dominant birth control pills?

A

flooding the body with extra estrogen clears acne for many acne-prone women by shutting down testosterone production in the ovaries.

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16
Q

when do most acne-prone women see post pregnancy acne flare?

A

acne often flares 90 days or so after pregnancy, and can also happen when getting off of birth control pills (from hormonal fluctuation)

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17
Q

what is comedogenic mean?

A

comedogenic refers to a substance’s ability to penetrate down into the pore and cause the formation of comedones.

18
Q

what is acne cosmetica?

A

acne caused by comedogenic ingredients in cosmetics. it can take up to 6 months to surface, often making it difficult for sufferers to make the connection. usually manifests as numerous whiteheads, sometimes a few of them may turn into inflamed pustules.

19
Q

how is zinc used in the treatment of acne

A

zinc helps cut down the inflammatory response to acne for many grade 3-4 sufferers. recommend 100mg or more per day for serious sufferers.

20
Q

explain the use of tetracycline (antibiotic) for acne

A

when tetracycline is taken orally, it eventually filters through to the skin and becomes bound to the protein in the stratum corneum, which can suppress the c. acnes bacteria.

many long term users experience toxic side effects: nausea, heartburn, yeast infections, brown stained teeth, or liver or kidney damage

21
Q

explain the use of cleocin (antibiotic) for acne

A

more potent antibiotic than tetracycline suppressing the c.acnes bacteria.

side effects: diarrhea and abdominal cramps, if not treated can lead to serious colitis.

22
Q

how does sun exposure help some acne sufferers?

A

it’s actually not helping, but it can have a drying effect on the skin which can be misconstrued as helpful. also the darker pigment from a tan can help blend the discoloration of lesions. it may even be the relaxation that comes with laying by the beach, etc.

23
Q

what is cryotherapy?

A

the science of applying cold to improve diseases is called cryotherapy (cryo=Latin for cold). freezing produces anit-inflammatory benefit reducing redness, and stimulating healing of papules, nodules, and cysts.

example=liquid nitrogen
icing daily 2x’s for 3-5 minutes for serious acne sufferers

24
Q

what are some other names for Vitamin A Acid?

A

tretinoin
retinoic acid
Retin-A (sold by Johnson & Johnson)

25
Q

what does vitamin a acid do for acne?

A

vitamin a acid (retin-a) successfully peels down the inside of the pore, unblocking and preventing further formation of impactions. it does not, however, combat the bacteria action in the pore.

26
Q

how does benzoyl peroxide work with clear acne?

A

benzoyl peroxide causes loosening of impactions and also fights the bacteria down in the pore. the benzoyl pulls the peroxide down into the pore where the c.acnes bacteria reside (anaerobic=can’t survive in the presence of oxygen)

bp causes peeling like vitamin a, it does not cause as much redness.

27
Q

the cornerstone of dr. fulton’s acne treatments are what?

A
  1. bp scrub cleansers
  2. vitamin a (speeds up peeling)
  3. extractions
  4. steroid injections into lesions (lessons scaring &reduces inflammation)
  5. cryotherapy
  6. topical antibiotics (erythromycin lotion) good for those who don’t want to peel as much
  7. systemic antibiotic for stubborn acne (tetracycline or minocycline)
  8. birth control pills (high estrogen)
  9. zinc (oral- to reduce inflammation in severe acne
28
Q

what is another name for Accutane?

A

isotrentinoin (causes a dramatic reduction of sebum production)
should only be used in the most severe cases of grade 4 cystic acne

29
Q

what is pseudofolliculitis barbi?

A

when coarse, curved beard hairs penetrate into the skin just before they would normally exit out of the follicle. very common in black men, and causes acne-like eruptions. treat like acne and use single blade with the grain & plain shaving cream (no menthol)

30
Q

explain in a nutshell what an acne regimen is and how it works.

A

benzoyl peroxide cleansers: kill bacteria
ice: reduces inflammation
AHA: strips off the dead skin cells
Vit-A: increase metabolism of the skin, speeds up peeling.

31
Q

what is the purpose of an acne treatment?

A

the purpose of an acne treatment is to irritate your skin, to cause peeling down inside the pore and zap the bacteria at the same time. it is normal to have some redness, stinging, irritation and peeling/flaking. it’s only too much if your face is very red, hurts and feels so tight that you feel like it will crack if you smile

32
Q

tips for acne with severe dry skin?

A

in the beginning, wash with lukewarm water and wait one or two hours before applying your active products (give your natural oils an opportunity to shield against the full effects). gradually shorten the time, eventually working toward applying right after washing.

33
Q

benzoyl peroxide warnings:

A

dont use a moisturiser with BP, it can migrate into the eyes and down onto the neck causing irritation. also, it does stain sheets/clothes

34
Q

when can i stop my regimen?

A

once you have achieved total clearing of acne, continue on the regimen for the next 3 months or so. at that point you can move down to a lower maintenance and probably stay clear until you reach your “burnout stage”. normally a BP cleanser twice daily will be good maintenance to keep you clear.

men burnout = early to mid 20’s
women burnout = mid 20’s to mid 40’s

35
Q

how does sulfur work on acne?

A

sulfur is a peeling agent, when used on its own it has questionable value. when mixed with BP, the BP becomes twice as effective.

36
Q

explain the difference between an enzyme and a peel

A

enzymes work by digesting and dissolving dead skin cells and imparting nutrients into the skin. they soften the skin and prepare it for more advanced treatments.

chemical peels do the same, only they penetrate more deeply to trigger various mechanisms to make new, healthier and younger skin cells. they in essence trick the body into making new skin.

37
Q

explain the effects of BP and Vit-A on black skin

A

benzoyle peroxide can darken (hp) black skin

vit-a lightens black skin. combining the two on black skin works well.

38
Q

when using retin-a perscription topical, which is the best type to use and why

A

retin-a gel or lotion is best, the retin-a cream usually has isopropyl myristate which may make acne worse.

39
Q

what is the main function of benzoyl peroxide?

A

kills bacteria in the pores

40
Q

what is dr. fulton’s favorite topical antibiotic (when needed in addition to bp for more antibacterial action)

A
erythromycin lotion (because it carries minimal side effects) or
clindomycin (Cleocin-T) some patients say this one is more effective.

he likes to use this at the beginning of treatment when the skin is acclimating to bp, but once the skin can tolerate the bp for longer periods of time, the erythromycin is stopped. it also works great on women with acne, and often times is enough to control the acne altogether along with mild bp at night.

41
Q

what are some of the common oral antibiotics prescribed for stubborn pustules or cysts?

A

teeetracycline
minocycline (Minocin)
erythromycin (EES-400)

42
Q

when is High-Estrogen birth control used as a possible therapy for acne?

A

women with chronic, persistent nodular scarring acne

example of high dose estrogen is Ortho-Novum 7-7-7
Demulen is a medium dose of estrogen

43
Q

for a woman who is starting birth control for acne, how long before she will see results?

A

it takes 2-3 months to see benefts, but give it 6 months. if you are clear after 6 months, stay on it for at least a year